Special Application TSKgel RPC Columns by Tosoh Bioscience

Manufacturer Tosoh Bioscience
4.2
/
5.0
  |  5 reviews
The TSKgel OligoDNA RP and TSKgel TMS-250 columns incorporate 5 μm or 10 μm spherical porous silica with 250Å pores to allow unhindered access by large oligonucleotides and proteins respectively. Product highlights TSKgel OligoDNA RP:   - Contains a monomeric C18 bonded phase that is not endcapped.    - Available in 4.6 mm id and 7.8 mm id (both 15 cm length)TSKgel TMS-250:   - Exhaustively and repeatedly reacted with trimethyl silyl groups.    - Standard nomenclature designates the bonded ph... Read more


Special Application TSKgel RPC Columns by Tosoh Bioscience product image
Special Application TSKgel RPC Columns
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Average Rating: 4.2
5 Scientists have reviewed this product

4 out of 5
Ease of use
4 out of 5
After sales service
4 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2021

  • Organization: Novartis



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Unfortunately, in the end twe chose a different column.
Rating: 4.7

  • Application Area: Antibody PepMap

"The column has worked so far, but due to some problematic peaks, the choice fell on a different column. "

Review date: 19 Mar 2021 | Special Application TSKgel RPC Columns
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Università degli studi di Firenze



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results and resolutions.
Rating: 5.0

  • Application Area:Size exclusion chromatography for separation and characterisation

"It was the right decision. These columns are the perfect choice for this application. Easy to use and store. Price/value really good."

Review date: 19 Mar 2021 | Special Application TSKgel RPC Columns
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Roche Diagnostics GmbH



  • Ease of use
    3 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
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Good results but lifetime vs. cost is often not well balanced.
Rating: 3.0

  • Application Area:HT SEC applications for therapeutic proteins

"Easy to use and good separation. But often experienced significant problems with lifetime."

Review date: 19 Mar 2021 | Special Application TSKgel RPC Columns
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Takeda/Baxalta Innovations GmbH



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
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Great results, especially for SEC analysis.
Rating: 3.7

  • Application Area:Protein analytics with size exclusion chromatography

"Excellent performance of methods and good reproducible results."

Review date: 19 Mar 2021 | Special Application TSKgel RPC Columns
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: Celon Pharma



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Very good for proteins.
Rating: 4.7

  • Application Area:Analysis of Antibody-Drug Conjugates

"These columns are a very good choice for ADC analysis as well as mAb and other protein analysis - reproducible results, well-shaped peaks and retention times stability are the main advantages for me, as an end user."

Review date: 07 Feb 2020 | Special Application TSKgel RPC Columns

The TSKgel OligoDNA RP and TSKgel TMS-250 columns incorporate 5 μm or 10 μm spherical porous silica with 250Å pores to allow unhindered access by large oligonucleotides and proteins respectively.

Product highlights

TSKgel OligoDNA RP:
   - Contains a monomeric C18 bonded phase that is not endcapped.
   - Available in 4.6 mm id and 7.8 mm id (both 15 cm length)

TSKgel TMS-250:
   - Exhaustively and repeatedly reacted with trimethyl silyl groups.
   - Standard nomenclature designates the bonded phase as C1.
   - Available in 4.6 mm id x 7.5 cm length.

Product Applications

TSKgel OligoDNA RP:
   - Specialty column for analysis and preparative purification of oligonucleotides (up to 500-mer), RNA and DNA-fragments.

TSKgel TMS-250:
   -  Specialty columns for protein separations.
   - The “wide-pore” TMS-250 packing can accommodate large proteins, such as aldolase (158 kDa).