SARS-CoV-2 Variant ValuPanel™ assays consist of separately delivered probes and primers that are designed for qualitative detection of specific SARS-CoV-2 mutations by genotyping using reverse transcription-polymerase chain reaction (RT-PCR). Each SARS-CoV-2 Variant ValuPanel consists of 2 BHQplus™ Probes and 2 primers for amplification and simultaneous discrimination between a specific mutation and the wild-type SARS-CoV-2 sequence.
For Research Use Only. Not for use in diagnostic procedures.
Several variants of SARS-CoV-2 have emerged bringing challenges to diagnostic tests and eradication efforts. Of particular significance are variants B.1.1.7 (first detected in the United Kingdom), B.1.351 (first detected in South Africa), and P.1 or B.1.1.28 (first identified in travelers from Brazil who arrived in Japan). The ability to quickly and reliably identify SARS-CoV-2 mutations will enhance the ability to gather crucial public health information regarding transmissibility kinetics of new variants, and the efficacy of vaccines and therapeutics.
SARS-CoV-2 Variant ValuPanel assays are for research use only, they are not intended for SARS-CoV-2 diagnosis. The SARS-CoV-2 Variant ValuPanel assays are intended for reflex tests only, designed for variant screening in respiratory tract samples that have previously tested positive for SARS-CoV-2 by diagnostic RT-PCR.