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Status:
Reviewer
Member since: 2021
Organization: NIH frederick
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- Ease of use
- After sales service
- Value for money
Useful for ChIP of thermally sensitive protein.
Application Area: ChIP
"Easy to use, specially for ChIP application I found highly reproducible data. this sonicator is also helpful when you are working with the immunoprecipitation of a protein whose binding to DNA is sensitive to heat."
Review date: 14 Jan 2022 | S220 Focused-ultrasonicators
Status:
Reviewer Member since: 2021
Organization: NIH frederick
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- Ease of use
- After sales service
- Value for money
Great and highly reproducible results.
Application Area:ChIP
"Easy to use with the high reproducibility of data. The length of DNA fragments is more accurate and in between the range."
Review date: 16 Dec 2021 | S220 Focused-ultrasonicators
Status:
Reviewer Member since: 2019
Organization: Corteva
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- Ease of use
- After sales service
- Value for money
S220 great for dna shearing
Application Area:DNA shearing
"Great instrument for DNA shearing. Fast and reliable. Service contract is a bit pricey."
Review date: 05 Feb 2019 | S220 Focused-ultrasonicators
The S220 Focused-ultrasonicator is a versatile, high power system engineered for pre-analytical sample processing with Covaris’ patented Adaptive Focused Acoustics® (AFA®). Utilizing a spherical acoustic transducer, specifically designed AFA Tubes, and advanced electronics, AFA delivers controlled energy precisely and accurately to sample volumes from 15 μl to 18 ml.
The versatility of the S220 Focused-ultrasonicator makes it possible to bring the advantages of AFA to numerous biological and chemical applications including, DNA, RNA, and chromatin shearing, tissue homogenization, cell lysis, compound dissolution, and particle micronization.
The S220 Focused-ultrasonicator is computer controlled by SonoLab™ Software, incorporating preset protocols for standard methods, such as DNA shearing to specific fragment lengths, and easy-to-use-tools for user-defined protocols. The S220 is also compatible with ActiveX control if required for more specialized customer-defined, laboratory automation applications.
Focused-ultrasonicators with AFA Technology operate at high frequencies (500KHz) and, therefore, unlike traditional low frequency laboratory sonicators. AFA is inaudible and does not require sound-proof boxes, hearing protectors, or other unusual precautions for their operation.
The S220 Focused-ultrasonicator is available in higher power (S220X) and robotic capable (S220R) configurations.
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