Nexera 40 Series UHPLC by Shimadzu Scientific Instruments Inc.

4.6
/
5.0
  |  7 reviews

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Nexera 40 Series UHPLC by Shimadzu Scientific Instruments Inc. product image
Nexera 40 Series UHPLC
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Average Rating: 4.6
7 Scientists have reviewed this product

5 out of 5
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2020

  • Organization: biodeal laboratories ltd



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great value for money and easy to use.
Rating: 5.0

  • Application Area: Analyze pharmaceutical drug substance and drug product

"Shimadzu Nexera series is an integrated machine that work with precision to deliver results for drug analysis in a fast and secure way. It is integrated with a LC solution software that makes data processing faster and easier. The support for the machine, repairs and spares are readily available making it good value for money. "

Review date: 25 Dec 2020 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: National University of Singapore



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great result.
Rating: 5.0

  • Application Area:Drug discovery system

"Nexera UHPLC and an LCMS-2020 mass spectrometer is a powerful choice for analysis."

Review date: 24 Dec 2020 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: ROLAND INSTITUTE OF PHARMACEUTICAL SCIENCES



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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A must have innovation for every analytical chemist.
Rating: 4.3

  • Application Area:Analytical chromatography

"AI and IoT based UHPLC is the best choice for pharmaceutical applications."

Review date: 24 Dec 2020 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: CLVCE



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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It is pleasure to work with this instrument.
Rating: 4.0

  • Application Area:Drug related compounds and impurities

"I obtain high quality LC data with good reproducibility. The sensitivity is perfect."

Review date: 26 Apr 2020 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: University of Arizona



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Good for testing purities. Hope it can be made better.
Rating: 4.3

  • Application Area:Separate mixtures of isomers and removing imourities

"It works well for separating the impurities from the analyte before using it for further analysis. However, lacks resolution for isomeric mixtures. 5' and 6' isomers are hard to separate."

Review date: 04 Mar 2020 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: The University of Arizona



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Good but could be better.
Rating: 4.7

  • Application Area:Separation

"The separation effectiveness is not as much as expected. Isomers are eluting at the same time but it can separate the other interfering compounds from the isomers that I am interested in and use for further analysis using CZE."

Review date: 04 Mar 2020 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: Analyticaone



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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A lot of features to guide the user to operate the system efficiently.
Rating: 5.0

  • Application Area:DOA

"The new nexara UPLC has many artificial intelligence features, such as pilot, weight sensor for solvents, and many others which make the use of the system very easy and straight forward. Shimadzu gives very good service and support - the team is available to support us any time."

Review date: 10 Feb 2020 | Nexera 40 Series UHPLC

The Nexera UHPLC series maximizes reliability and uptime with fully unattended workflows that span from startup to shut-down. Operators can set the Nexera to start up at a specified time, so that it can complete auto-purge, equilibration, baseline checks and system suitability in advance, and be ready for analysis before they arrive at the lab. In addition, FlowPilot ramps up the flow rate gradually, reducing the possibility of damage to columns. The Nexera also has auto-diagnostics and auto-recovery capabilities that allow it to monitor pressure fluctuations to check for anomalies. 

With remote mobile phase monitoring and integrated consumables management, the system maximizes uptime and reliability. Real-time monitoring of mobile phase levels allows lab personnel to efficiently run batches and respond accordingly if there isn’t enough mobile phase before starting a run. In addition, Nexera tracks consumable usage and sends alerts when parts need replacing, allowing users to keep the system running at peak performance. The Nexera UHPLC series allows analysts to confirm parameters and monitor chromatograms in real time directly from a web browser on their smart device. 

The Nexera UHPLC increases efficiency by automating workflows and maximizing throughput analysis. The SIL-40 autosampler can process the entire injection cycle time in as little as seven seconds, and continuous analysis can be carried out on up to 44 MTPs (using 3 plate changers). The SIL-40’s plate changers enable non-stop temperature-controlled analysis of thousands of samples. The Nexera automatically blends mobile phases at any set ratio, which speeds up the preparation of buffer solutions and the dilution of solvents. Because it prepares the exact amounts required for analysis, the Nexera reduces waste and labor.