mosquito® LV Nanolitre Liquid Handler
Accurate low volume (nL - µL) pipetting
An excellent companion for your "Nano dispensing"
Genomics
From a user experience, Mosquito LV is a reliable and robust machine. The precision and reproducibility delivered by the instruments is exceptional, a perfect fit for our single-cell protocols.
Review Date: 6 Nov 2023 | SPT Labtech
Nanoliter scale reactions, awesome!
Synthetic biology
SPT Labtech’s mosquito does what it promises, robust high precision low volume liquid handing.
Review Date: 15 Mar 2021 | SPT Labtech
Essential for high throughput screening.
Nanolitre liquid handling system
A critical piece of equipment that speeds up serial dilutions of multiple compounds and easily tranfers to assay plates. Perfect for high throughput screening and easy to make new protocols.
Review Date: 22 Nov 2019 | SPT Labtech
Great results!!
X-ray crystallography
The TTP Labtech Mosquito HTS is an amazing instrument that allows us to screen through hundreds of crystallographic conditions in a fraction of the time and material that it would take to do manually. Customer service has always been helpful and prompt with any questions or service.
Review Date: 4 Jun 2019 | SPT Labtech
Plan to purchase again!
Assays
Very easy + user friendly. Use to make assay ready plates+ stamp from mother plates. Plan to purchase again!
Review Date: 14 Feb 2019 | SPT Labtech
Great tool for small labs.
Small molecule drug discovery (compound management)
Very versatile and easy to use. Anyone can program this and it is the ideal walk up station.
Review Date: 4 Feb 2019 | SPT Labtech
Every laboratory must have one.
Molecular biology
Excellent product, very robust. Easy to use, accurate results.
Review Date: 22 Jan 2019 | SPT Labtech
Wish I could take it with me everywhere I go!
Molecular Biology
Extremely happy with the equipment. User friendly, straightforward software. People with no background in automation can use it. We have achieved reproducible results.
Review Date: 9 Mar 2017 | SPT Labtech
Would definitely recommend and would buy it again.
Compound Management and Screening
The Mosquito delivers consistent and reliable liquid dispensing for a variety of different plate formats and plate types.
Review Date: 8 Mar 2017 | SPT Labtech
Great Instrument, cannot imagine our lab without it
Drug Discovery
This is an amazing instrument. It offers the performance of an acoustic dispenser but at a much lower price point. It is a good instrument for a smaller lab that needs to dispense in the 1uL – 25nL range and allows the use of any plate type. For us, we needed something that could fit into our workflow and didn't require the need for changing plate types and the Mosquito was the perfect choice.
Review Date: 22 Feb 2016 | SPT Labtech
mosquito® LV offers an accurate and easy to use solution which can be applied to miniaturising any assay within an automated, high throughput setting leading to significant savings on precious reagents and time. In conjunction with mosquito HV, the scale of assay miniaturisation can be expanded to cover the range of 25 nL to 5µL.
Benefits of the mosquito LV include:
- Accuracy – outstanding accuracy with < 2% error throughout the volume range
- Precision – unrivalled precision with CVs of < 3% throughout the volume range
- Speed of set up – quick set-up with no washing
- Flexibility of sample type – precise pipetting across a wide range of liquid viscosities with no changes in instrument setting required
- Serial dilution wizard – simple programming using a serial dilution wizard incorporated into the software
- Minimal dead volumes – access all of your sample: mosquito LV leaves dead volumes of under 0.3 µL per well
- Compatibly – compatible with all SBS format 96-, 384- and 1536-well plates
- Integration options – can be easily integrated with the mosquito plate processor (MoPP) into a larger screening system
- Cost savings – the ability to use smaller volumes of valuable protein resulting in cost savings and enabling a larger number of screening conditions to be studied
- Small footprint – bench-top instrument
- Ease-of-use – simple robust and walk-up-and-use bench-top instrument
mosquito LV can be used for miniaturizing a wide range of applications which require a volume range of 25 nL – 1.2 µL, including:
- Preparation of “assay ready” plates for compound screening
- Serial dilutions in miniaturised volumes for generation of concentration response curves
- Plate reformatting, including transfer between different plates types (96-, 384- and 1536-well plates)
- Plate replication
- Molecular biology based applications such as: next generation sequencing, DNA, RNA extraction and PCR/qPCR preparation
Using TTP Labtech’s mosquito liquid handler with Mosaic sample management software
Mosaic sample management software tracks liquid handling operations performed by instruments or users within a Mosaic workflow. Pipetting operations such as individual well-to-well transfers, plate replication, transfers from microtubes to plates, etc. can be achieved in a variety of ways using Mosaic. This application note gives an overview of how the TTP Labtech mosquito liquid handling platform can be integrated with Titian Software's Mosaic to fulfil your liquid handling needs.
SPT Labtech accelerates discovery with high-precision liquid handling automation
With 25 years of trusted innovation, SPT Labtech continues to advance scientific discovery through intelligent, high-precision automation. In this SelectScience interview, Caroline Wickramasinghe, Senior Product Manager for Core Liquid Handling, highlights two of the company’s flagship innovations: the dragonfly® discovery and mosquito®. Together, these liquid handling systems exemplify how intuitive software, robust engineering, and scalable automation are empowering scientists to adapt to new workflows, such as 3D cell culture, efficiently and with exceptional reproducibility.
This video was filmed at SLAS 2026.
From Academia to Applications Scientist - Inspired by Technology
Field applications scientist Chris Waddling, of SPT Labtech Inc., began his career as a crystallographer in academia at UCSF. In this video, Waddling describes how he was inspired by the revolutionary technology of the mosquito liquid handler to pursue a career in industry, where he could help others to advance their research with cutting-edge lab products.
This interview was filmed as part of our coverage of SLAS2019 - see other video highlights here >>
Miniaturize Your Genomics Assays with SPT Labtech’s True-Positive Displacement Technology
Soheila Vaezeslami, PhD, Sr. Field Application Scientist, SPT Labtech, explains how the mosquito range of automated liquid handlers incorporate true-positive displacement technology, enabling the accurate transfer of liquid in the nano- to microliter range. Hear how the system enables genomics researchers to save on both sample preparation cost and sample input, as well as providing an easy-to-use design, optimal for low, mid to high throughput applications.
Sustainability in the lab: Progress, opportunities, and the path forward
This guest editorial from SPT Labtech introduces the Labtech Unplugged podcast series, sharing real-world stories of labs worldwide implementing sustainable practices
Drug Discovery Video Playlist: 6 Experts Share Research & Technology Insights
Watch exclusive highlights from the show floor at SLAS2019 as we find out about the latest technologies innovating life sciences discovery
Overcoming the Sample Preparation Bottleneck in Your NGS Workflow: Experts Share Advice in Upcoming Webinar
Learn about solutions for automated low-volume liquid handling for cost-effective NGS library preparation and single cell genomics






























