Status:
ReviewerMember since: 2022
Organization: Shinshu University, Department of Regenerative Medicine
It looks smart, and we want to use right away.
Application Area: Analyze iPSC crdiomyocytes
"W just bought the instrument."
Status:
ReviewerMember since: 2022
Organization: Shinshu University, Department of Regenerative Medicine
Great, can't live without this instrument soon.
Application Area:Analyze network burst of iPS-Neuron
"We got the instrument just 2 weeks ago. So, no results. However, MEA-plate is good for culture of iPS-Neuron at this moment. We will try using Maestro Edge to analyze network burst of iPS-Neuron in the next week."
Status:
ReviewerMember since: 2022
Organization: Purdue University
Excellent customer service, software is intuitive, analysis is quick and easy
Application Area:Electrophysiology
"We have published three papers so far with data collected and analyzed from this machine and software. The customer service team answered our questions promptly and concisely. Even re-using the plates up to three times, we get reproducible results."
Status:
ReviewerMember since: 2022
Organization: The University of Maryland, Baltimore
Amazing system, even greater team at Axion to support you in using it
Application Area:Analyze neuronal responses to stimulation
"The Axion system has been a great tool for our stimulation experiments as it allows us to test many stimulation protocols and measure responses through metrics provided such as mean firing rate and bursting frequency. The system is easy to use and comes with software updates as well. Importantly, the team at Axion is available to support and also provide guidance in how best to use the system to explore your hypotheses. The Axion system also allows for exporting time series data for analysis using custom MATLAB scripts, allowing for freedom and flexibility in working with the data to glean insights from it."
Status:
ReviewerMember since: 2020
Organization: Tohoku Institute of Technology
Easy-to-use, high throughput electrophysiological platform.
Application Area:Neuronal toxicology, pharmacology
"The Maestro MEA system is extremely easy to operate and acquire data. The user-friendly software is very nice and visualizes neural activity from multiple wells in real-time, and it is intuitive. Our lab members can easily operate and smoothly conduct experiments with drug and electrical stimulations. Since the temperature and CO2 environment are well maintained, long-term continuous measurement is possible. In addition, the MEA plates delivered are well managed, and customer support is very good."
Status:
ReviewerMember since: 2020
Organization: Korea Institute of Science and Technology
Great for rapid screening of neuroactive drugs.
Application Area:Extracellular recording of neural activity from brain slices
"The system and software are easy to use. Produce high-quality and reproducible data. More suitable for cell culture-based recording of extracellular electrophysiological activity, but can also record neural activity from brain slices with appropriate setup."
Status:
ReviewerMember since: 2020
Organization: Sungkyunkwan university
Works well, we are satisfied with it!
Application Area:iPSC derived Cardiomyocyte function assay
"We purchased this product for analyzing cardiomyocyte and neuron functions. It's easy to use it and works well. Customer service is also good so our lab is satisfied with Mastro Edge."
Status:
ReviewerMember since: 2020
Organization: sogang univ.
Strongly recommend!
Application Area: iPSC derived brain organoid function assay
"First of all, I like that it is very easy and simple to use, so anyone can use it without special skills. Also, various kinds of tools available that can be used to efficiently analyze the signal of the sample are very useful to me. I also liked the services, such as answering questions kindly."
Status:
ReviewerMember since: 2020
Organization: Seoul National University
Best MEA system.
Application Area:Human iPSC-derived cardiomycytes
"Excellent multi-electrode array system. Everything is easy to use, including analysis and reporting. It consists of all-in-one hardware and everything you need for analysis is implemented in the programs."
The Maestro Edge multiwell MEA and Impedance system allows you to capture the complex biology of your cells. Whether monitoring the kinetics of cellular growth and death or recording the activity of excitable cells; the Maestro Edge can help you record it noninvasively, in real time, and with software tools to make analysis quick and painless.
Don’t miss a datapoint. Capture the complexity of your live-cell assay from start to end. While traditional end point assays may perturb or destroy your cells in the process, the Maestro Edge automatically collects data without disturbing the cells. With fully integrated incubation, the Maestro Edge’s small benchtop footprint conserves space in the lab and requires no additional incubator.
With multiwell microplates, multiple assays can be performed simultaneously.
The Maestro Edge allows you to record multielectrode array (MEA) data from electrically active cells (e.g. neurons, cardiac cells, muscle cells, retina, and zebrafish) as well as cell proliferation, death, morphology, attachment, barrier function, and signaling using impedance. No matter the assay, the environmentally controlled chamber will record physiological responses without perturbing the cells.
The Maestro Edge platform delivers an easy-to-use, compact cellular analysis system suitable for any lab.
KEY FEATURES
Measure cellular activity label-free and real-time - The Maestro Edge detects key parameters of neural network activity, cardiac functionality, and cell growth, death and attachment.
Precisely control the cells environment - Cells are a product of their environment. Maestro Edge has a smart environmental chamber that finely controls temperature and CO2 while rejecting electrical noise and mechanical vibrations.
Connect to your network - 384 electrodes simultaneously record from your cells with the Neural, Cardiac, and MEA Viability modules. Now you can understand life’s circuitry label-free and in real time in 6- or 24-well plates.
Continuous cell monitoring - 96 simultaneous live recordings from your cells with the Impedance module. Track cell proliferation, morphology, and viability in real time.
See your cells - Sometimes you just want to look at your cells under a microscope. Maestro’s CytoView patented transparent circuit technology allows cell visualization and assay multiplexing.
Control cellular activity - Recreate specific patterns of cellular activity using electrical stimulation or light pluses (with the Lumos optical stimulation system).
Start your assay with the push of a button - “One button setup,” means temperature and CO2 levels automatically adjust on plate docking. Plate usage is logged via an integrated plate barcode scanner for convenient experiment tracking.
Monitor the kinetics of your biology on your smartphone - No need to be in lab. With the Impedance module, track changes in cell proliferation, viability, and cell killing over minutes or weeks.
MEA Applications include but are not limited to:
Impedance-based assays include but are not limited to: