Member since: 2017
Organization: Syngene International ltd
Alternate mAb standard highly recommended.
Application Area: Intact mAb mass check standard for LCMS
"This particular mAb standard is not as reliable standard as many people think. We have experience with this particular product. It shows lots of variations from run to run. Highly heterogeneous compound. As per highest source, 10 to 20 Daltons mass variations is expected with this. Sample stability is questionable. Coming from a reliable source, we came to know that even Waters is looking for alternate mAb standard due to the variability."
Analysis of intact proteins by MS is a powerful approach for protein identification and assignment of protein modifications. The Intact mAb Mass Check Standard is a LC-MS standard used as a qualitative tool for intact mass analysis. This standard is designed to be used for routine MS optimization, system setup and performance testing.