In vitro VOC Sampling by Owlstone Medical

Discovering and validating biomarkers for disease is a key stage in developing valuable and effective diagnostic tests for clinical applications. You may already have a detailed understanding of the biology of your disease of interest but how can you go about translating that into the clinic?

If you’ve already conducted a clinical trial, in vitro sampling could be an efficient route to achieving the level of validation you need to achieve regulatory approval and widespread acceptance.

Our in vitro sampling pipeline supported by our Breath Biopsy Services can help you to identify volatile organic compounds (VOCs) produced by your laboratory samples that have the potential to be effective biomarkers for non-invasive clinical breath testing. We provide an optimized detection process supported by expert VOC analysis and identification that provides high confidence candidate biomarker discovery ideal for clinical translation.

Features

• Identify clinically relevant VOC biomarkers using optimized HRAM GC-MS
• Examine drug mechanisms and pharmacodynamics
• Generate evidence to support clinical studies or clinical approval
• Relate clinical results to underlying biological processes
• Compare disease site VOCs to exhaled breath VOCs on the same Breath Biopsy Platform

Applications

• Cell culture headspace sampling
• VOC products of in vitro biochemical reactions
• Detect ex vivo tissue VOC emissions

Breath Biopsy Products and Services are for research use only. Not for use in diagnostic procedures.