The Ansh Labs' Total IGFBP-4 ELISA and Intact IGFBP-4 ELISA kits are quantitative three-step sandwich immunoassays.
The ratio of Total to Intact IGFBP-4 concentration measured in individual subjects over time will help normalizes the IGFBP-4 variability between subjects and also increase the detection rate of increased PAPP-A activity in myocardial infarction subjects. Also useful in research related to cancer studies, hypertension, diabetes, cardiomyopathy, osteoarthritis, aging and longevity studies, and growth hormone deficiency.
Neither assay cross-reacts to IGF-I, rat IGF-I, IGFBP-3, IGFBP-3/IGF-1 complex and IGFBP-2 at 1000 ng/ml concentration. Detects bovine and equine IGFBP-4 when tested in serum samples.
The Total IGFBP-4 assay has an analytical measurable range of 15 – 233 ng/mL and is sensitive to 1.61 ng/mL. The Intact IGFBP-4 assay has an analytical range of 7-1200 ng/mL and is sensitive to 1.62 ng/mL. The incubation times are between 2 and 2.5 hours at room temperature.
Research Use Only within the United States.
Ansh Labs, located just south of Houston Texas, is an FDA registered manufacturer of diagnostic test kits, antibodies, antigens, and proteins. Our scientists are experts in immunoassay development and have developed some of the most challenging hormone assays helping to advance research and clinical diagnostics in reproductive function, growth disorders, metabolism, and more.