HALO^® Columns by Advanced Materials Technology

Higher Efficiencies.  Faster Analysis.  Reduced Back Pressures.

HALO^® LC columns take a different path towards the goal of improving separation efficiencies and more quickly, without the extreme back pressure consequence of sub 2 µm fully porous particles using their novel Fused-Core^® technology.  

HALO^® columns are manufactured using Fused-Core^® particle technology which delivers hyper-fast chromatographic separations while avoiding the reliability issues so often associated with fast HPLC.

As mobile phase flow rates are increased to speed-up a separation, the slow mass transfer of solute molecules inside the particles can limit resolving power. HALO^® column particle technology with its solid core and porous shell addresses this limitation by providing an incredibly small path for diffusion of solutes into and out of the particles, thereby reducing the time solute molecules spend inside the particles and minimizing a major barrier to fast chromatographic separations.

With a wide range of innovative phase chemistries and pore size optimization, HALO^® columns are designed for improving both small and large molecule separations.   HALO^® columns are available in multiple particle sizes to enhance performance in all LC instrumentation.   They can turn a standard HPLC system into a high-speed workhorse as well as improve efficiencies from UHPLC and LCMS analysis.

This little HALO^® Fused-Core^® particle started one large revolution and its technology has been accepted as the modern standard in high performance LC and LCMS separations.