EZ DNA Methylation-Lightning™ Kit by Zymo Research

"We experience very high-quality results with this product and find the results reproducible and very reliable. We have been using Zymo methylation kits for years now, first the gold kit and now we are mainly using the lighting kit. Tech support is always very helpful and responsive whenever we have questions."

"The lightning kit is super-easy to use, efficient and reliable resource for bisulphite conversion. Great tool for methylation research."

"Easy to use, easy to scale down to single cell platforms and automation. Great results!"

"EZ DNA Methylation-Lightning Kit is friendly to user product and provides rapid and full DNA conversion for epigenetic applications. The conversion is done in ~1h; and in our hands the quality of conversion is the same as for Gold kit. Converted DNA is then easily purified and is ready for subsequent PCR. Contrary to other conversion kits (e.g. Gold or Direct), Lighting reagent is ready-to-use and does not require solubilization of the reagent in different buffers."

"This is our "go-to" kit for bisulfite. Fast, efficient and inexpensive. Seems to work as well or better than all other kits we've tried."

"It’s easy to use but the only problem is it produces less product, requiring me to use more columns."

"I have been using this kit for several years. All the reagents are included in the kit and ready-to use, which means the whole process can be done in two hours. The input DNA can go down to 100 pg, which is really important if my tissue samples are very limited. The output DNA is suitable for illumina DNA methylation array or next generation sequencing. The results are always reliable and reproducible."

"This kit is the best one I have used for DNA bisulfite conversion. It is easy and quick. The product quality is good and reproducible. I used the product for EPIC methylation array, sequencing, and COBRA assay - the results are great."

"EZ DNA methylation lightning kit is the easiest kit for the bisulfite conversion and the methylation analysis. It gives a good yield of bisulfite converted DNA and the time required for this is very less."

"High quality and reproducible results on next generation sequencing samples. Easy to use and high recovery efficiency. "

"High reproducibility but low yield. In protocol, it's possible to convert 2ug of DNA but for high effectiveness, they recommend 500ng, which is not enough to check for one time MSP for the first time. "

"The only product which has given satisfactory yield of 100% converted DNA. PCR worked in first shot."

"The product covers our laboratory's every need, in an easy and cost-effective manner. It's really simple to use and you can always rely on customer service for help"

"Nothing can replace Zymo products and the accuracy that I am getting from using this kit. Cost wise and work time wise, Zymo is user friendly. Also if we face any issues, Zymo technical support and the complete manual with the troubleshooting help us to figure out the solution. When compared with some top brand company kits, Zymo never loses its own standard in methylation and other molecular research. Due to its uniqueness and result accuracy, it's always good to stand with Zymo products. I am even an active user of some more of their products like Direct-zol™ RNA MiniPrep and DNA Clean & Concentrator™, which are always excellent products for research use. In epigenetics, ZYMO IS THE BEST AND WILL BE THE BEST, which you can trust blindly. I always strongly recommend to my colleagues to go for Zymo products for epigenetics work. Zymo always holds its name "The Epigenetics Company". I have no negative comments or negative reviews for Zymo products. Until now, I have never contacted technical support of Zymo because I have never faced any big issue in working with Zymo kits. MiniPrep kit is extremely easy to use and time saving. Compared to other products it is cheaper and less time consuming. I have also had very good results isolating different RNA sizes compared to conventional methods with trizol and, importantly, I always got the best purity. The microelution was key here. Zymo products are more reliable and I never used any software until now so I can’t say anything much about that. Overall, Zymo products are user friendly, more reliable and worth spending money on than any other kits. Also, online chat technical support is more useful at timely situations. I depend on Zymo more for epigenetics work and epigenetics applications. Zymo is the only company which can reach the research standard."

"The kit is very easy to use, the quick guide protocol gives clear instructions, and so far our results have been high quality and consistent. "

"The product is easy to use and the process does not take much time. The quality of the result product is satisfying"