DNA encoded library (DEL) components
Accelerating drug discovery with better oligos
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Accelerating drug discovery with better oligos
DNA encoded libraries (DEL) are a rapidly growing drug discovery platform. Synthesizing a DNA encoded library requires the assembly of unique molecules linked to unique identifying DNA sequences that serve as barcodes. Subsequently, hits (candidate compounds) are identified by sequencing the DNA barcode. The use of high-quality oligos is essential to the success of DEL synthesis.
High quality oligos for high quality libraries
LGC offer standard and custom DEL oligo components (headpieces, tags and primers) and is a trusted partner with many organizations that are synthesizing DEL by split and pool, encoded self-assembly, DNA templated chemistry, and other synthesis techniques.
By understanding your needs and working collaboratively, LGC aim to advance DEL technology together.
Better results
Confidence that DEL synthesis will work the first time
- Over 35 years of experience in nucleic acid synthesis
- 100% QC – each oligo is QC’d by LC/MS to verify quality and identity
- Manufactured in an ISO 9001 certified facility
Reproducibility
Consistent performance in library synthesis
- Large scale synthesis capacity allows for single batch manufacturing, removing the need to pool multiple batches
- Proprietary in-house engineered synthesizers
- Automated liquid handling
- Complete control of raw material supply chain and quality
Flexibility
Get the oligos you want in the format you want
- Multiple standard and custom synthesis scales
- Multiple delivery formats
- Custom modifications
- Custom conjugation chemistries
Combining DNA encoded libraries with machine learning to accelerate drug discovery
This webinar will offer highlights of various DNA encoded library (DEL) technologies with a focus on DNA recorded technologies applied to machine learning (ML). Discover how Anagenex combines their ML model with an iterative learning loop of lab experiments, to produce a feedback mechanism that is designed to create a robust drug discovery process. This significantly accelerates the process of drug discovery at a fraction of the price of non-DEL routes by allowing researchers to explore a vast chemistry space, and create effective screening models.
Key learning objectives
- Learn how building high quality DELs and understanding what information your DNA sequence provides you is important to combining DEL and ML.
- Understand how DEL and ML enable the creation of iterative libraries that enhance results.
- Discover how DEL and ML can identify high quality chemical matter for challenging targets.
Who should attend?
- Companies and academic groups focusing on DEL.
- Companies and academic groups wanting to learn how to implement DEL technologies and how to couple DEL with machine learning.
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
Can combining machine learning with DNA-encoded libraries revolutionize drug discovery?
Learn how drug hunters are leveraging advanced algorithms and DNA barcoding tools to bring targeted medicines to patients sooner
