Derivatization Reagents for Silylation by Sigma-Aldrich Supelco

Supelco provides high quality derivatization reagents for silylation.Silylation is the most widely used derivatization technique. Functional groups that present a problem with gas chromatogaphy detection - hydroxyl, carboxylic acid, amine, thiol, phosphate - can be derivatized by silylation reagents. Silylation involves replacement of the acidic hydrogen with an alkylsilyl group, for example, -SiMe3.Silylation derivatives are generally less polar, more volatile and thermally more stable. The cho... Read more


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Derivatization Reagents for Silylation

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Supelco provides high quality derivatization reagents for silylation.

Silylation is the most widely used derivatization technique. Functional groups that present a problem with gas chromatogaphy detection - hydroxyl, carboxylic acid, amine, thiol, phosphate - can be derivatized by silylation reagents. Silylation involves replacement of the acidic hydrogen with an alkylsilyl group, for example, -SiMe3.

Silylation derivatives are generally less polar, more volatile and thermally more stable. The choice of a silylating reagent is based on its reactivity and selectivity towards the compound, the intended application, the stability of the derivative, and the abundance/nature of reaction byproducts.

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Derivatization Reagents for Silylation by Sigma-Aldrich Supelco product image

Derivatization Reagents for Silylation

Manufacturer Sigma-Aldrich Supelco

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