CRISPR/CAS9 Gene Editing of Human Induced Pluripotent Stem Cells (iPSCs)
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CRISPR Edited iPS Cell Lines
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Induced pluripotent stem cells (iPSCs), have the capacity to give rise to differentiated progeny arising from of all germ layers of the body including: ectoderm, endoderm, and mesoderm. The ability to expand patient derived human iPSCs in vitro and subject them to cell-type specific differentiation protocols is the basis for generating “disease-in-a-dish” cellular models for basic stem cell research and drug-discovery applications.
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