Collagenase from Clostridium histolyticum by Merck KGaA, Darmstadt, Germany

Manufacturer Merck KGaA, Darmstadt, Germany  |   Model: C5138  |  Available Worldwide
  |  1 reviews
Release of physiologically active rat hepatocytes tested, Type IV, 0.5-5.0 FALGPA units/mg solid, 125 CDU/mg solid  

Collagenase from Clostridium histolyticum by Merck KGaA, Darmstadt, Germany product image
Collagenase from Clostridium histolyticum

Merck KGaA, Darmstadt, Germany

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Average Rating: 4.7
1 Scientist has reviewed this product

5 out of 5
Ease of use
4 out of 5
After sales service
5 out of 5
Value for money

  • Status:

    Advanced Reviewer
  • Member since: 2016

  • Organization: M.S. University of Baroda, vadodara

  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Very effective. Tissue digestion is easy and faster.
Rating: 4.7

  • Application Area: Cancer stem cells culture

"It is good value-of-money and made my research easy."

Review date: 15 Jul 2022 | Collagenase from Clostridium histolyticum

Collagenase from Clostridium histolyticum has been used:

  • in the preparation of collagenase solution for the digestion of tumor tissues
  • as a supplement in phosphate-buffered saline for the digestion of extirpated mesenteric fat tissue
  • as a supplement in Roswell Park Memorial Institute-1640 medium (RPMI-1640) for the digestion of colon segments
  • for the digestion of endometrium tissues
  • in the preparation of enzyme A and enzyme B for the digestion of decapsulated testes

Collagenase has been used in the preparation of arterial tissue for the study of Advanced Glycosylation End Products (AGE). The enzyme has also been used along with other proteases for the disaggregation of human tumor, mouse kidney, human brain, lung epithelium and many other tissues. It is also effective in liver and kidney perfusion studies, digestion of pancreas, and isolation of nonparenchymal hepatocytes. This enzyme is tested for suitability for the release of hepatocytes, at approx. 1 mg/mL conc., in a total volume of 100 mL for each rat liver.