CLARIOstar® Multimode Microplate Reader by BMG LABTECH

Manufacturer BMG LABTECH  |  Available Worldwide
4.7
/
5.0
  |  30 reviews
The most versatile, high-performance monochromator-based multi-mode microplate reader


CLARIOstar® Multimode Microplate Reader by BMG LABTECH product image
CLARIOstar® Multimode Microplate Reader
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Average Rating: 4.7
30 Scientists have reviewed this product

5 out of 5
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money


Great multimode plate reader
Rating: 5.0

  • Application Area: Plate reader

"We already have a Fluostar which is in a way the old version of this machine. The ClarioStar is a multimode plate reader (abs, Fluo, lumi) very easy to use, powerful and very sensitive. The big plus for us considering the Fluostar is that the machine has a monochromator which is an optical device that selects a wavelength of light or a range thereof. So we are not limited anymore with filters!"

Review date: 10 Aug 2018 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2012

  • Organization: Pharmaxis



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Happily bought BMG readers twice already
Rating: 5.0

  • Application Area:HTS and Mode of Action studies

"We bought the Clariostar after having used the Fluostar for several years, having had nothing or very little to complain about. The machine provides all the sensitivity and versatility we (small Pharma) need, and a powerful and user friendly analysis software (Mars). I can (and did) recommend this instrument as a valid alternative to more expensive equipment."

Review date: 23 Jul 2018 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: UCL



  • Ease of use
    3 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
seems to do the job, yet to be seen the full spectrum
Rating: 3.7

  • Application Area:Protein analysis

"Not the end-user; but being he purchaser, aftersales care seems ok up to now."

Review date: 19 Jul 2018 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 1989

  • Organization: Montana Molecular



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Highly recommend this instrument for live cell fluorescent assays
Rating: 5.0

  • Application Area:Genetically encoded fluorescent assays for Cell Stress and GPCR activity

"We use the Clariostar fluorescence plate reader to detect simultaneous changes in our red and green fluorescent sensors. In our current project we combine either our red fluorescent CADDis sensor for cAMP or our red fluorescent DAG sensor with our green arrestin signaling sensor in the same cells to determine agonist bias in a single assay. The Clariostar is particularly well-suited for these multiplex assays in living cells because of the excellent optical path design. Fluorescence Intensity measurements are straightforward and the onboard software is reliable and intuitive. The instrument is compact and we install on a bench top where it has performed flawlessly after several years of heavy use."

Review date: 24 Jun 2018 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: imperial college



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Great instrument.
Rating: 4.7

  • Application Area:Real time fluorescence analysis on DNA displacement reaction

"It's very easy to operate and the software is powerful."

Review date: 18 Jun 2018 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: ENAMINE Ltd.



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Perfect instrument with wide range of use.
Rating: 5.0

  • Application Area:High Throughput Screening

"Great flexibility, ease of use. Provides high-quality results. Would highly recommend."

Review date: 14 Mar 2018 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Sanford Burnham Prebys Medical Discovery Intitute



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Can't be beat for ease of use and rapid enzyme kinetics.
Rating: 5.0

  • Application Area:Enzyme kinetics

"I use the CLARIOstar mainly for enzyme kinetics. I like the fact that the CLARIOstar can measure at a very short intervals. This is very important to me since a lot of the enzymes I use are very good at cleaving the fluorescent substrates that I'm using. I also like the CLARIOstar because it can read at multiple gains. So if I don't know the well that will generate the most fluorescence I can set a low, medium and high gain and pick the best for my application. The software is very easy to navigate for both the CLARIOstar and the MARs analysis software. Just recently our institutes old plate reader that was used for dual luciferase assays went down. The CLARIOstar is now being used by our institute for all the dual luciferase assays. Set up was easy and all the new users were up and running in about 30 minutes. I know BMG tech support is only a phone call away and is always willing to help. If they don't know the solution to my problem while I'm on the phone with them, they call back as soon as they figure out the solution. I could not be happier with the choice I made to purchase the CLARIOstar over other fluorescent plate readers."

Review date: 29 Nov 2017 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Inetertek CRS



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
Great service
Rating: 3.7

  • Application Area:Sample analysis

"Very fast service, great team, more than satisfied"

Review date: 16 Nov 2017 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: University of Surrey



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Fantastic reader.
Rating: 5.0

  • Application Area:Cell signalling

"The UK team of BMG are by far the best sales team I have worked with in three different countries. The CLARIOstar is an excellent reader for the money. It is extremely versatile and the sensitivity blows most other readers on the market out of the water."

Review date: 19 Oct 2017 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Iowa State University, College of Vet Med



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Motivates me to go to lab everyday
Rating: 5.0

  • Application Area:RT-QuIC, Fluorescence and absorbance, kinetic assays, and pretty much everything

"Efficient, high quality, versatile and ease to use"

Review date: 12 Jul 2017 | CLARIOstar® Multimode Microplate Reader


  • Status:

    Reviewer

  • Member since: 2016

  • Organization: University of Modena and Reggio Emilia



  • Ease of use
    3 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
Good results also with the monochromator.
Rating: 3.0

  • Application Area:Cell Signalling Analysis

"It is a good machine, allowing a deep investigation of the cell signaling induced by different agonists upon binding to their receptors. The interface is user-friendly after understanding a few key points of the software. "

Review date: 22 Jun 2017 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: NIDDK/NIH



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Great product and highly recommended.
Rating: 4.7

  • Application Area:fluorescence measurement, such as FRET, et al.

"Easy to set up. Reproducible measurements, versatile and flexible for different measurements, overall data quality is good, and the results are satisfying."

Review date: 09 Feb 2017 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: 490 BioTech, Inc.



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
A very well designed instrument with an excellent software interface
Rating: 4.7

  • Application Area:Toxicology assays using human cell lines

"The CLARIOstar has been a work-horse instrument in our lab and has performed flawlessly. The software interface is excellent and enables easy programming of assay parameters and very straightforward analysis of resulting data. Technical assistance from BMG has been first-rate."

Review date: 09 Feb 2017 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: University of Bristol



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Very easy to use, and very versatile
Rating: 5.0

  • Application Area:Protein binding assays

"Very easy to use, and has a range of applications."

Review date: 07 Feb 2017 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: CDI



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Great results with this instrument; we are happy!
Rating: 5.0

  • Application Area:Cell-based assays

"This plate reader is very versatile and powerful. We are impressed with the software and interface - simple and intuitive. For our everyday luminescence and fluorescence assays, this instrument does the job very well."

Review date: 06 Feb 2017 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Ruhr-Universität Bochum



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
A great product with a very good user concept.
Rating: 4.7

  • Application Area:Luminescence, Absorbance, Fluorescence Spectroscopy

"A very easy to use multi-mode reader. Sensitivity was good for all our measurements so far (e.g. ThT Assay for fibril formation). Different configuration options (e.g. addition of automatic injection, larger T-range). The software is easy to handle and allows to configure a lot of presets for various applications. The data analysis software supports all necessary standard evaluations and allows an easy export for data handling with other software. Makes it also suitable for teaching and use in education. "

Review date: 23 Jun 2016 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: PHOST'IN SAS



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Very correct money rating.
Rating: 4.0

  • Application Area: Cytotoxicity Assay

"I recommend it to others. Easy to use for many applications (optical density, Cytotoxicity, etc.) "

Review date: 25 May 2016 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: BIO-GENE



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
The best system I have ever used.
Rating: 5.0

  • Application Area:Cell based assay

"The Clariostar is the best system I have ever used so far, the system is very flexible and easy to use. Great technical support. "

Review date: 23 Nov 2015 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: Department of Biochemistry



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:Real time fluoresecence production

"We purchased the CLARIOstar with the gas control module. As a plate reader, the CLARIOstar shows a fantastic performance with fluorescence, luminescence and UV measurements. The monochromator system of filters gives a great flexibility with very minor loss in sensitivity when compared to normal filter settings. The gas control unit offers a unique versatility, since you can either use the device as a conventional plate reader or to monitor production of fluorescent proteins in living cells with high precision. We are therefore very satisfied with this device and we strongly recommend it. "

Review date: 16 Oct 2015 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: Bellbrook Labs



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0
"A great instrument to measure FP. This reader is amazing for measuring polarization. It is extremely sensitive. Also the ability to fine tune the bandwidth makes it a great instrument. "

Review date: 12 Oct 2015 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2012

  • Organization: Torrey Pines Institute for Molecular Studies



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0
"The CLARIOstar is very easy to use, super sensitivity and the speed in many different technologies is outstanding and versatility in fluorescence assays. I have demo'd both the PHERAstar FS and the Clario and their performance is similar. Clario definitively wins for the price tag."

Review date: 12 Oct 2015 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Expert Reviewer

  • Member since: 2012

  • Organization: Exact Sciences



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0
"The instrument and its stackers work well for high throughput screening, allowing fast and consistent read times for microplates. FP comparisons to other readers found the ClarioStar to have higher resolution, require fewer flashes, and result in lower CVs per plate. BMG is very fast at answering any questions and worked with us on any custom requests. "

Review date: 06 Oct 2015 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: I-STEM



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.7

  • Application Area:Compounds effect in stem cell screening

"The Clariostar is a really robust machine and with great flexibility. The control interface is easy to use and allows a lot of customization. It has a very good sensitivity. And spectral scanning option is very useful. In stacker mode, its speed is necessary in our screening campaign. Moreover, its price is really competitive."

Review date: 18 Aug 2015 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2014

  • Organization: University of Cambridge



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Rating: 4.7

  • Application Area:Fluorescence and absorbance-based assays

"The Clariostar is the most versatile plate reader so far, and we use it for many different applications."

Review date: 18 Feb 2015 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: UCLA



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:DLR, Florescent Reporter, ELISA assays

"We purchased a Clariostar reader recently to be a workhorse for our labs plate reading needs, and it has performed excellently. Compared to our old microplate reader, this machine is much easier to use and maintain, and not having to change out filters every time we run a new assay is wonderful. We got great install and setup support when we purchased as well. The spectral scanning feature, adjustable band pass, and price really sold us on the BMG reader over another Tecan system we were looking at. We are very happy with our purchase. "

Review date: 18 Feb 2015 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2014

  • Organization: University of Pavia



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.7

  • Application Area:Binding and Activity Assay Development; Drug discovery

"The instrument is versatile for a broad range of applications and reading modes. We currently use it for fluorescence polarization, intensity, UV-ABS readouts. The use of a monochromator instead of filters or optic modules really makes the instrument flexible and met the needs of all the research projects in the lab, as each of us uses different molecules/fluorophores and detection modes. We had a minor issue with the software, but it was promptly solved by the BMG support (they are excellent as for "customer care"). Quite user-friendly and quite easy setups. The idea of the "modularity" of the machine is helpful as well: we got our custom machine with for FP, injectors as major modules, with the awareness of the chance to upgrade the machine with new modules instead of buying a new plate reader. Very good and competitive quality/price value."

Review date: 06 Oct 2014 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2014

  • Organization: Mission Therapeutics



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:Drug Discovery

"A long awaited multipurpose plate reader that does not require filters. I have used it for a variety of assay systems; fluorescence intensity, fluorescence polarisation, absorbance and found it easy to use. The injectors are a great addition for kinetic assays."

Review date: 08 Sep 2014 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2014

  • Organization: University of Cambridge



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.3

  • Application Area:Various single read and time resolved fluorescence assays

"It was about time that BMG had a monochromator based platereader, to combine the flexibility of that sort of instrument with their general high standards of instrument quality and customer support. Our Clariostar works well, except for some small issues with the software, potentially stemming from compatibility problems with the setup of our operating system. But the customer support (UK) is as always excellent. Due to the fundamental design changes, it probably wasn't possible to keep the same filter format as for the filter-based platereaders (the Clariostar still needs filters for polarization experiment and at short wavelengths), so the filters can't be interchanged, which is a pity. Overall, it is probably the most versatile platereader on the market, and the modular build up (can be upgraded with high temperature option up to 65C, luminscence, injectors etc.) gives you flexibility on the price."

Review date: 18 Aug 2014 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: Beckman Coulter



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Rating: 4.3
"BMG delivers excellent service and good value with the unit. Unlike competitors, the software is very easy to use and lets you get the most out of each plate. "

Review date: 25 Feb 2014 | CLARIOstar® Multimode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2014

  • Organization: Takeda Pharmaceuticals International Co.



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Rating: 4.7

  • Application Area:Assay Development

"It is a very flexible instrument with good software. It is suitable for assay development (96/384 well, multiple reading modes). Tuneable not filters. For low/medium throughput, not an HTS machine."

Review date: 14 Feb 2014 | CLARIOstar® Multimode Microplate Reader

The high-performance CLARIOstar® microplate reader from BMG LABTECH with monochromators, spectrometer, and filters. A multimode reader with revolutionary monochromator technology.

Advanced LVF Monochromators™ offer cutting-edge technology, such as linear variable filters and a linear variable dichroic mirror, for higher performance fluorescence and luminescence assays including FRET and BRET. There is no compromise when it comes to sensitivity and flexibility, making the CLARIOstar® one of the leading microplate readers on the market.

Features of the CLARIOstar®:

  • A continuously adjustable bandwidth from 8 to 100 nm allowing more light for excitation and emission, resulting in greater sensitivity
  • No stray light thanks to the LVF Monochromators™ design means greater sensitivity
  • Top and bottom reading for fluorescence and luminescence assays using monochromators or filters
  • Combine filters and monochromators in the same measurement for higher performance in any fluorescence or luminescence assay
  • High-speed, full spectrum UV/Vis absorbance (220 to 1000 nm in under 1 second per well)
  • A dedicated, high-energy laser for AlphaScreen® and AlphaLISA® assays


Direct optics – as opposed to fiber optics – provide higher light transmission, significantly increasing performance in assays such as fluorescent proteins.

Now with independent O2 and CO2 control for live cell assays.

The CLARIOstar multi-mode microplate reader from BMG LABTECH is now even more versatile! The new Atmospheric Control Unit (ACU) allows independent, simultaneous control of both O2 and CO2 within the microplate reader chamber. Ranging from standard cell growth assays to cytotoxicity assays, the ACU provides the optimal environment for any live cell-based assay.