CLARIOstar^® Plus Multi-mode Microplate Reader by BMG LABTECH

"It’s great."

"Fluorescence Polarisation assays are quick, easy and reliable. We use our Clariostar constantly and find it essential for binding assays"

"It made experiments very easier. Also, the neccesary time is deceased a lot."

"Getting our CLARIOstar plus installed was quick and simple and it immediately enhanced the capacity of our lab. The software is intuitive and the hardware is very robust. Many off-the-shelf assay kits work straight away with the default protocols meaning very short optimisation time. It also has a great customisation ability to develop unique assays with no published precedent."

"We use this plate reader for absorbance, fluorescence, FRET, FP, and luminescence. It works great and is highly reproducible for all applications. Good sensitivity. Easy to set-up experiments and export the data via Excel sheets. We also have the injector module that is great for semi-fast reaction kinetics. This is a work-horse of an instrument."

"It is very easy to use and has a very wide range of applications for different assays. BMG has always given me a really good care after purchase since our first product in 2013."

"Easy to use, it also has a spectra mode which is awesome if we don't know whether some reagents can affect the absorbance or fluorescence of samples."

"Using the CLARIOstar for LDH assays makes cell death measurements efficient. The interface is easy to use and the set up of experiments using the software is intuitive. Creating templates for repeat use makes experimental set up effortless and export of data is uncomplicated. Through continual use of this machine I have yet to find something that I find unnecessarily complex or not user friendly."

"It is the most flexible plate reader I have used. I am so impressed with its sensitivity and flexibility, especially in live cell based assays."

"The EDR (Enhanced Dynamic Range) technology is extremely useful for fluorescence measurements. The free unlimited software is very helpful and highly appreciated. The data software offers a lot of convenient functions."

"CLARIOstar reader is very easy to use, intuitive and the machine comes with a very helpful manual and tons of examples that help you to optimize your experiments. Furthermore the vendor provides software for the results of the analysis that is very handy. The only complaint I have is about the help service that the website offers. In my group we wrote several times but we didn’t get any answers. Apart from this, the machines is very useful since you can run different experiments (Fret, Tr-fret, FP, fluorescence intensity etc) that you can set it up easily in your lab without the need to hire experts to do it. Once set up you can perform the experiments in a short time."

"Pretty flexible and sensitive; User-friendly reader; Provide very professional after-sales support."

"The CLARIOstar instrument is flexible to use and the software is simple, fast and accurate. Data is very easy to access and analyze. it is really a helpful too!"

"CLARIOstar multimode plate reader is the ideal reader for assay development. It has high sensitivity and flexibility. It is a little expensive, but it is worth having it in the laboratory. It gives us accuracy in what we do."

"I mainly use this product to run biochemical screening assays. Setting up protocols for screening is user friendly and easy. The CLARIOstar produces rapid and accurate results making it a very useful tool to have in the lab."

"Easy to use and I can run a kinetic assay with no worries about dynamic range; It's a powerful microplate reader, includes TRF, Alpha, FP and so on, almost all of my assays can be done on it."

"The CLARIOstar instrument is easy to use and the software is simple, fast and accurate. Data is very easy to access and analyze. Justin is a massive help too!"

"The CLARIOstar has many great applications that have helped immensely with my work. It's quick to set up, easy to use and the output is very user friendly. Justin is always on hand whenever I need to answer all questions and help me out."

"The Clariostar is easy to use and Justin is an excellent rep, always avaliable to help with questions and applications."

"The CLARIOstar is an excellent plate reader with multi-modal function. I have used it for fluorescence polarization applications and found the user interface intuitive and easy to set up. It also comes with MARS analysis software which allows me to do quick analyses on the data produced."

"I use both the BMG Pherastar and Clariostar for a range of assays. Their flexibility and sensitivity are enabling for many of the assays I do and the software interface make them easy to use and to teach grad studnets to use. The after-sales service, paritcularly for assays development from BMG has been excellent, their staff have a genuine interest in science done by their instrument users."

"I've used the CLARIOstar quite a few times in the teaching labs! The software is super user-friendly which is great for teaching students and they're pretty robust ie. Not super fragile that'll break easily with students. They are self-explanatory and it was easy to figure out what to do the first time we used it!"

"Excellent quality, robust, top service and easy to use. I recommend all their products very highly. I have been a user since 2004."

"Excellent instrument. Incredibly reliable. Intuitive to operate. Great customer care."

"The CLARIOstar is a superb multi-functional instrument that I have used in many different aspects of my research. I have produced high quality data that has been published. It is my favorite instrument in terms of ease of use and the many various experimental techniques available in the one machine. Every lab needs one!"

"FP SD is excellent. Very easy interface."

"The CLARIOstar Plus replaced the CLARIOstar. It's very high quality and overall it looks like a modern plate reader. Moreover, it is easy to use and I love MARS with advanced calculations. Thank you BMG for sending us the CLARIOstar Plus."

"A very high quality modern plate reader and easy to use. Nearly 1000 readings in a year and it works like a clock. The service and support is superb."

"Happy to work with CLARIOstar Plus. This is the first time about powerful microplate reader which can do everyrything - fluorescence, luminescent and alphascreen too."

"CLARIOStar Plus is one of the most innovative, easy to use instrument I have used in a long time. It has a extended dynamic range and this ability makes the instrument a life-saver. I have nothing but great experience with its customer support and they have helped me with anything from a minor issue to a large problem. The support team works fast, efficiently and are very knowledgeable."

"The BMG CLARIOstar Plus is a robust, reliable and highly sensitive plate reader. Both software and hardware are precise, powerful and consistent. The ongoing support from BMG is second-to-none!"

"The CLARIOstar Plus is very easy to use. It's fairly intuitive, so that for the most common applications one can sit down and get through a protocol without a manual or technical support. For more complicated applications, our regional sales manager, EJ, has been just a phone call away. He's been extremely helpful and knowledgeable, and has made sure we get the most that we can out of our plate reader."

"We have found the BMG platereaders excellent machines to use, with easy to use software that does the job very well. We have multiple users and the capacity to have individual logins and templates is a real bonus. The Clariostar is an excellent tool with the capacity to 'tune' flourescence to our needs which increases the useability and ease use capacity enhancing our research."

"Very robust and versatile instrument, extremely useful in our multi-users facility. Good value for money. Excellent sales, application and technical support team."

"The CLARIOstar combines sensitivity with flexibility, which is essential for assay development. Multiple wavelength windows can be utilized and can be optimised for the assay in question. The after sales support has always been exceptional."

"The CLARIOstar Plus Multi-mode Microplate Reader is fantastic. The model is very easy to operate, including relatively intuitive software with helpful data analysis (Mars)."

"Really versatile equipment, I've used it for different purposes, the commands are self-explanatory, it doesn't require deep knowledge of spectrometry to operate it and I always got reproducible results."

"Well built and accurate machine, does exactly what we need to a high standard. Delivery, installation and training were excellent and helped get our company started."

"High quality and easy to use. It is a little expensive."

"Only one instrument for absorbance, fluorescence and chemiluminescence needed in the lab which saves space and time. The software is easy to use when doing measurements. For calculations a deeper understanding of the software is necessary, but is provided by the customer service which is very helpful and offers regular visits in order to help with any issues the user might have."

"Versatile, easy to use, robust (no instrument failures so far), good analysis software Description of the anisotropy mode in the manual could be a bit better The fluorescence intensity signal seems very sensitive to the sample volume (e.g. slight differences in the volume give large errors) Not sure if this is better with other readers, but found it less pronounced with a Tecan"

"We already have a Fluostar which is in a way the old version of this machine. The ClarioStar is a multimode plate reader (abs, Fluo, lumi) very easy to use, powerful and very sensitive. The big plus for us considering the Fluostar is that the machine has a monochromator which is an optical device that selects a wavelength of light or a range thereof. So we are not limited anymore with filters!"

"We bought the Clariostar after having used the Fluostar for several years, having had nothing or very little to complain about. The machine provides all the sensitivity and versatility we (small Pharma) need, and a powerful and user friendly analysis software (Mars). I can (and did) recommend this instrument as a valid alternative to more expensive equipment."

"Not the end-user; but being he purchaser, aftersales care seems ok up to now."

"We use the Clariostar fluorescence plate reader to detect simultaneous changes in our red and green fluorescent sensors. In our current project we combine either our red fluorescent CADDis sensor for cAMP or our red fluorescent DAG sensor with our green arrestin signaling sensor in the same cells to determine agonist bias in a single assay. The Clariostar is particularly well-suited for these multiplex assays in living cells because of the excellent optical path design. Fluorescence Intensity measurements are straightforward and the onboard software is reliable and intuitive. The instrument is compact and we install on a bench top where it has performed flawlessly after several years of heavy use."

"It's very easy to operate and the software is powerful."

"Great flexibility, ease of use. Provides high-quality results. Would highly recommend."

"I use the CLARIOstar mainly for enzyme kinetics. I like the fact that the CLARIOstar can measure at a very short intervals. This is very important to me since a lot of the enzymes I use are very good at cleaving the fluorescent substrates that I'm using. I also like the CLARIOstar because it can read at multiple gains. So if I don't know the well that will generate the most fluorescence I can set a low, medium and high gain and pick the best for my application. The software is very easy to navigate for both the CLARIOstar and the MARs analysis software. Just recently our institutes old plate reader that was used for dual luciferase assays went down. The CLARIOstar is now being used by our institute for all the dual luciferase assays. Set up was easy and all the new users were up and running in about 30 minutes. I know BMG tech support is only a phone call away and is always willing to help. If they don't know the solution to my problem while I'm on the phone with them, they call back as soon as they figure out the solution. I could not be happier with the choice I made to purchase the CLARIOstar over other fluorescent plate readers."

"Very fast service, great team, more than satisfied"

"The UK team of BMG are by far the best sales team I have worked with in three different countries. The CLARIOstar is an excellent reader for the money. It is extremely versatile and the sensitivity blows most other readers on the market out of the water."

"Efficient, high quality, versatile and ease to use"

"It is a good machine, allowing a deep investigation of the cell signaling induced by different agonists upon binding to their receptors. The interface is user-friendly after understanding a few key points of the software. "

"Easy to set up. Reproducible measurements, versatile and flexible for different measurements, overall data quality is good, and the results are satisfying."

"The CLARIOstar has been a work-horse instrument in our lab and has performed flawlessly. The software interface is excellent and enables easy programming of assay parameters and very straightforward analysis of resulting data. Technical assistance from BMG has been first-rate."

"Very easy to use, and has a range of applications."

"This plate reader is very versatile and powerful. We are impressed with the software and interface - simple and intuitive. For our everyday luminescence and fluorescence assays, this instrument does the job very well."

"A very easy to use multi-mode reader. Sensitivity was good for all our measurements so far (e.g. ThT Assay for fibril formation). Different configuration options (e.g. addition of automatic injection, larger T-range). The software is easy to handle and allows to configure a lot of presets for various applications. The data analysis software supports all necessary standard evaluations and allows an easy export for data handling with other software. Makes it also suitable for teaching and use in education. "

"I recommend it to others. Easy to use for many applications (optical density, Cytotoxicity, etc.) "

"The Clariostar is the best system I have ever used so far, the system is very flexible and easy to use. Great technical support. "

"We purchased the CLARIOstar with the gas control module. As a plate reader, the CLARIOstar shows a fantastic performance with fluorescence, luminescence and UV measurements. The monochromator system of filters gives a great flexibility with very minor loss in sensitivity when compared to normal filter settings. The gas control unit offers a unique versatility, since you can either use the device as a conventional plate reader or to monitor production of fluorescent proteins in living cells with high precision. We are therefore very satisfied with this device and we strongly recommend it. "

"A great instrument to measure FP. This reader is amazing for measuring polarization. It is extremely sensitive. Also the ability to fine tune the bandwidth makes it a great instrument. "

"The CLARIOstar is very easy to use, super sensitivity and the speed in many different technologies is outstanding and versatility in fluorescence assays. I have demo'd both the PHERAstar FS and the Clario and their performance is similar. Clario definitively wins for the price tag."

"The instrument and its stackers work well for high throughput screening, allowing fast and consistent read times for microplates. FP comparisons to other readers found the ClarioStar to have higher resolution, require fewer flashes, and result in lower CVs per plate. BMG is very fast at answering any questions and worked with us on any custom requests. "

"The Clariostar is a really robust machine and with great flexibility. The control interface is easy to use and allows a lot of customization. It has a very good sensitivity. And spectral scanning option is very useful. In stacker mode, its speed is necessary in our screening campaign. Moreover, its price is really competitive."

"The Clariostar is the most versatile plate reader so far, and we use it for many different applications."

"We purchased a Clariostar reader recently to be a workhorse for our labs plate reading needs, and it has performed excellently. Compared to our old microplate reader, this machine is much easier to use and maintain, and not having to change out filters every time we run a new assay is wonderful. We got great install and setup support when we purchased as well. The spectral scanning feature, adjustable band pass, and price really sold us on the BMG reader over another Tecan system we were looking at. We are very happy with our purchase. "

"The instrument is versatile for a broad range of applications and reading modes. We currently use it for fluorescence polarization, intensity, UV-ABS readouts. The use of a monochromator instead of filters or optic modules really makes the instrument flexible and met the needs of all the research projects in the lab, as each of us uses different molecules/fluorophores and detection modes. We had a minor issue with the software, but it was promptly solved by the BMG support (they are excellent as for "customer care"). Quite user-friendly and quite easy setups. The idea of the "modularity" of the machine is helpful as well: we got our custom machine with for FP, injectors as major modules, with the awareness of the chance to upgrade the machine with new modules instead of buying a new plate reader. Very good and competitive quality/price value."

"A long awaited multipurpose plate reader that does not require filters. I have used it for a variety of assay systems; fluorescence intensity, fluorescence polarisation, absorbance and found it easy to use. The injectors are a great addition for kinetic assays."

"It was about time that BMG had a monochromator based platereader, to combine the flexibility of that sort of instrument with their general high standards of instrument quality and customer support. Our Clariostar works well, except for some small issues with the software, potentially stemming from compatibility problems with the setup of our operating system. But the customer support (UK) is as always excellent. Due to the fundamental design changes, it probably wasn't possible to keep the same filter format as for the filter-based platereaders (the Clariostar still needs filters for polarization experiment and at short wavelengths), so the filters can't be interchanged, which is a pity. Overall, it is probably the most versatile platereader on the market, and the modular build up (can be upgraded with high temperature option up to 65C, luminscence, injectors etc.) gives you flexibility on the price."

"BMG delivers excellent service and good value with the unit. Unlike competitors, the software is very easy to use and lets you get the most out of each plate. "

"It is a very flexible instrument with good software. It is suitable for assay development (96/384 well, multiple reading modes). Tuneable not filters. For low/medium throughput, not an HTS machine."