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Chromium Single Cell Immune Profiling

10x GenomicsAvailable: Worldwide

Chromium Single Cell Immune Profiling provides a multiomic solution to your immunology questions. Analyze full-length, paired B-cell or T-cell receptors, surface protein expression, antigen specificity, and gene expression, all from a single cell.

10x Genomics

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Description

Multiomic cytometry: Highly sensitive detection of 5’ mRNA with antigen specificity and phenotyping.

Complete immune repertoire: Paired, full-length Ig sequence, including isotypes, and T-cell receptor α/β.

Immune mapping: Combine immune repertoire with antigen specificity at single cell resolution.

Streamlined data analysis: Explore and visualize clonotype information with easy-to-use software.

One-day lab workflow: From sample to sequencing-ready library in one day, with an option for an automated workflow.

Scalable solutions: From standard experimental needs to higher throughput for comprehensive studies, find the kit that fits your research.

Application NoteLife Sciences

Deep characterization of a CAR T-cell product using targeted single cell transcriptomics

Deep characterization of a CAR T-cell product using targeted single cell transcriptomics. Download 10x Genomic's latest white paper to learn how targeted single cell transcriptomic profiling can help accelerate CAR T-cell therapy development by measuring transduction efficiency and comprehensively characterizing the infusion product, cell by cell. Learn more about how targeted single cell gene expression analysis of a CAR T-cell infusion product can provide:

  • Increased sensitivity and precision over traditional approaches, like flow cytometry
  • Deeper characterization of immune phenotypes, including cell type and functional state
  • Insight into measuring anti-CD19 CAR transduction efficiency using targeted baits for the scFv region of the CAR vector


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