Xevo TQ-S micro Triple Quadrupole Mass Spectrometer

This application note demonstrates an improvement in the current LC-MS method for vitamin D analysis. It demonstrates the determination of total vitamin D by individually measuring the vitamin D and previtamin D in food products. Previtamin D was directly measured in the total vitamin D analysis, eliminating the error that could arise from not measuring previtamin D. This method will be less affected by the heating history of food products.

In this application note, Waters present the use of a simple sample extraction and d-SPE clean up where the resulting extract is analyzed by UPLC-MS/MS or APGS-MS/MS in a manner that complies with Canadian regulatory requirements. A single workflow for the multi-residue analysis of pesticides in cannabis is demonstrated.

In this application note, Waters presents the use of a simple sample extraction and dispersive solid phase extraction (dSPE) clean-up procedure, followed by UPLC-MS/MS analysis, for rapidly monitoring the Oregon pesticide list.

Waters Acquity UPLC-MS/MS and Xevo TQ-S micro systems are designed to improve pesticide detection for ProVerde laboratories, helping scientists ensure customer safety for medical marijuana products.

In this application note, Waters presents the use of a simple sample extraction and dispersive solid phase extraction (dSPE) clean-up where the extract is analysed by UPLC-MS/MS and/or GC-MS/MS for rapidly monitoring pesticides and mycotoxins in cannabis matrix.

In this brochure, Waters presents solutions for plant-to-product cannabis testing to help regulated laboratories consistently deliver accurate results.

Voted the Top Cannabis Testing Lab in Canada in 2017, Anandia provides a range of quality control, pesticide detection, and breeding tool services. Anandia employ analytical instrumentation and software from Waters to improve testing capabilities, helping scientists ensure customer safety and product integrity for current and future cannabis products.

This application note presents an analytically sensitive, accurate and precise measurement of corticosteroids and androgens in serum, for clinical research.

In this application note, the development of a multiresidue method for the routine determination of 190 pesticide residues in various fruit and vegetable matrices using UPLC-MS/MS is described. White grapes and green beens were selected for this application due to their relatively increased complexity, since they contain chlorophylls which are known to affect the extraction efficiency of pesticides from food matrices. A generic QuEChERS sample extraction procedure was used to extract the pesticides from the samples, followed by a rapid and high resolution UPLC separation and trace level detection of pesticides using the Xevo TQ-S micro.

Interferences by matrix components can be challenging when measuring serum levels of vitamin D metabolites by LC-MS/MS, particularly lysophosphatidylcholines. They are challenging to remove during sample preparation and difficult to separate chromatographically. This white paper describes an approach for method optimization using the Oasis PRiME HLB solid phase extraction plate, from Waters.

The opioid epidemic in the US is a severe public health crisis, with increasing misuse, addiction, and overdose deaths. Central to tackling opioid dependence are dedicated treatment plans using opioid substitute therapy. However, as the crises evolves into its now fourth wave, different regions are exposed to different concoctions of drugs and so a more personalized approach to evaluating compliance with therapy is required.

Speaking with Dr. JP Canner, Chief Scientific Officer and Laboratory Director at Gravity Diagnostics, we explore how this state-of-the-art CAP-accredited and CLIA-certified laboratory is expanding its drug testing menus to respond to regional drug use patterns seen as part of its clinical toxicology services.

Prof. Chris Elliott from the Institue of Global Food Security, at Queen's Univerity Belfast describes what is involved in his research into food safety and integrity. He also highlights the key technologies he and other food scientists are using in their research.

As a leading clinical LC-MS/MS solutions partner, Waters is a trusted provider of in vitro diagnostic medical devices, consumables, informatics, and support services for high performance LC-MS/MS systems. Learn how and why University Hospital of South Manchester has introduced Waters LC-MS/MS IVD instrumentation into their busy clinical laboratory.

Enhancements for the Waters Xevo G2-XS QTof, SYNAPT XS and SELECT SERIES Cyclic IMS instruments accelerate biomedical and pharmaceutical research

Designed for quantitative analysis, Waters' full portfolio of TQ MS systems makes high performance and routine analysis accessible, robust, reliable

We look back at the biggest stories and the best content from our analytical chemistry communities

We take a look at some of the most common sources of food contaminants and how to detect them simply, accurately and effectively

Learn how a lab in the US is using enhanced chromatography and spectrometry techniques to analyze cellular metabolites in urine linked with future cancer risks

Prepare for the American Society for Mass Spectrometry(ASMS) Annual Meeting by discovering the many applications of mass spectrometry – from pesticide detection to imaging for cancer therapy

Discover how Waters technology is facilitating this pioneering study