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Viridis SFC Columns

Introducing Viridis SFC columns for purification incorporating our patented Prep OBD column technology. Combining state-of-the-art media manufacturing with the industry leading column technology, Viridis Supercritical Fluid Chromatography (SFC) columns bring a new level of reproducibility to the world of laboratory scale purification. Viridis SFC columns are available for analytical and preparative chromatography as: Virid…

Waters

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Description

Introducing Viridis SFC columns for purification incorporating our patented Prep OBD column technology.

Combining state-of-the-art media manufacturing with the industry leading column technology, Viridis Supercritical Fluid Chromatography (SFC) columns bring a new level of reproducibility to the world of laboratory scale purification.

Viridis SFC columns are available for analytical and preparative chromatography as:

  • Viridis SFC 2-Ethylpyridine columns
  • Viridis SFC Silica columns
Application NoteSeparations

Extraction and Isolation of a Natural Product from Schisandra Berry Extract using SFE and SFC

Berries of schisandra (Shisandra chinensis) have been widely used for medicinal purposes in traditional Chinese medicines for centuries. The berries contain a wide variety of organic compounds with dibenzo[a,c]cyclooctadiene lignans being of particular interest. This application note demonstrates the feasibility of using the Prep100q SFC System as a tool for isolating schisandrin A from dry schisandra berries extract using supercritical fluid extraction (SFE).


Application NoteSeparations

Isolating Trace Impurities for Structural Elucidation in a Commercial Fungicide Formulation Using Preparative SFC

Trace impurities in synthetic products that interact with human end users or may have an undesirable environmental fate are regulated by various government agencies such as FDA and EPA. As a result, impurity separation and their structural identification are important research functions for many industries, including pharmaceutical, agrochemical, food, and consumer products. This application note describes a workflow to achieve full structural elucidation of trace impurities that can be implemented using preparative supercritical fluid chromatography to isolate trace impurities.


Application NoteSeparations

Improving the Productivity in Isolating a Naturally Occurring Bioactive Compound Using Supercritical Fluid Extraction and Preparative Supercritical Fluid Chromatography

This application demonstrates the use of SFE and prep SFC to holistically improve the productivity in isolating a low-polarity, bioactive compound from a complex natural product extract. The SFE alleviated the sample complexity prior to analysis and purification, thereby improving sample loading and reducing solvent use in the ensuing chromatography. The SFE extract also lends itself well for SFC analysis and purification.

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