timsMRMS

Dive deeper into chemical complexity

Enhanced specificity and selectivity with TIMSTIMS enables the detection of isomeric diversity with the addition of accurate collision cross section data (CCS) for greater molecular specificity… all at the same time.

Versatility

Perhaps one of the greatest attributes of MRMS is its versatility. The new timsMRMS is equipped with both MALDI and API sources (e.g. ESI, APCI, etc.). Structural characterization can be performed via Q-CID and/or ExD fragmentation. It is the ultimate MS 'tool box' for research. 

Unrivaled MS performance

Ultra-high performance extends to mass resolving power, dynamic range, and mass measurement accuracy. These are the primary figures of merit needed for the detection and confident identification of unknowns in complex mixtures.

Approachability

The timsMRMS features the Maxwell magnet which requires no liquid cryogens and allows the system to be sited in almost any MS laboratory. New instrument control automation, like 'auto shim', allows the researcher to focus on the chemical problem, rather than complex operation modes.

The next generation in MRMS technology

Core to the timsMRMS is the integration of trapped ion mobility spectrometry (TIMS) to MRMS - the world’s most powerful mass spectrometer. This combination enables researchers to tackle extreme complexity, adding greater depth and confidence. 

• Dual MALDI / ESI source - The timsMRMS features a dual ion source for both MALDI and ESI. The change between ionization modes is fast and effortless. 
• Smartbeam 3D and microgrid technology for high spatial resolution imaging. Smartbeam 3D is Bruker’s latest advancement in MALDI based imaging and features the highest spatial resolution to date within the Bruker family of imaging platforms and detection of isomeric diversity. 
• Proprietary gated TIMS for accurate CCS val separation (selectivity) with a unique molecular identifier – CCS (specificity).
• High capacity collision cell that enables continuous accumulation of selected ions (CASI) and Q-CAD. The ion capacity of the newly designed collision cell matches that of the MRMS detector cell, maximizing S/N and time efficiency. 
• ParaCell with 2xR capability. MRMS is synonymous with ultra-high performance, and this have never been easier to achieve than with the timsMRMS. At its core is the ParaCell detector in combination with the high-fidelity magnetic field of the Maxwell magnet. Ultra-high resolution and accuracy is effortless, making eXtreme performance routine.
• Heated cathode – accessibility to all modes of ExD fragmentation adding to the arsenal of structural tools that are available on the timsMRMS.