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SYNTAX System

DNA ScriptAvailable: Worldwide

DNA-on Demand with benchtop convenience and same-day results.

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Reviews

Average Rating 5.0

|2Scientists have reviewed this product

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Excellent results and can’t survive without this instrument

 

Average Rating 5.0

Application Area:

Genetic engineering and biotechnology

Product is environmentally friendly and cost effective and cost efficient

Review Date: 25 Mar 2022 | DNA Script

DNAScript is a game changer in oligo synthesis.

 

Average Rating 5.0

Application Area:

Life Sciences, synthetic biology

Innovative machine for the synthesis of DNA oligos, outstanding customer service, and really fast to obtain the product.

Review Date: 24 Jan 2022 | DNA Script

Introducing the SYNTAX System, the first DNA printer powered by enzymatic synthesis. Designed for speed, reliability and ease of use, the SYNTAX System enables you to produce your own high quality ssDNA oligo, up to 120 mer, overnight and in house. It eliminate external suppliers dependency and delivery constraints, allow to keep your IP in house, and it gives you the ability to respond faster, iterate with confidence, and eliminate uncertainty from your workflows.

System Capabilities

  • Automated synthesis with little hands on time for run preparation
  • Intuitive software to design, set up and visualise runs
  • Performed by Enzymatic DNA Synthesis: reduce chemical waste , no need of specialized infrastructure
  • From 96 to 384 oligos synthesised in parallel
  • Synthesize oligos overnight for next-day use

Oligo Specifications

  • Oligos from 15 nt to 120 nt oligos
  • Default 5’-phosphate
  • Oligos ready-to-use right off the SYNTAX (desalted and in aqueous solution)
  • Oligo quality on par with gold‑standard providers
  • From $0.11 by nucleotide

Applications

Ready-to-use oligos for molecular biology and genomics applications, including

  • PCR, dPCR
  • qPCR primers and probes
  • Sanger sequencing
  • site-directed mutagenesis
  • Gene assembly

Brochures

Product brochuresLife Sciences

SYNTAX System

DNA Script introduces a new paradigm in oligo synthesis, the SYNTAX System, powered by Enzymatic DNA Synthesis (EDS) technology to accelerate life science innovation. Designed for ease of use, productivity, convenience, control, and confidentiality, the SYNTAX System enables automated nucleic acid synthesis within a benchtop solution. In this application note, you can find all applications and benefits of the technology.

White PapersLife Sciences

Enzymatic DNA synthesis

This resource describes DNA Script's Enzymatic DNA Synthesis (EDS) technology, which enables automated, in-house production of DNA oligonucleotides using engineered enzymes rather than traditional phosphoramidite chemistry. The approach is designed to provide faster access to custom DNA while supporting a range of genomics and molecular biology applications.

Resource details:

Resource type: Whitepaper
Page count: 4
Read time: 6 mins


Application NoteLife Sciences

Gene assembly

DNA Script demonstrated successful assembly of EGFP and mRFP reporter genes using oligos produced with its Enzymatic DNA Synthesis (EDS) technology and SYNTAX™ System. The study shows high gene assembly success rates and accelerated timelines, enabling sequence-verified clones in as little as three days.

Resource details:

Resource type: Application note
Page count: 12
Read time: 18 mins


Application NoteClinical Diagnostics

SARS-CoV-2 spike protein mutagenesis

DNA Script demonstrated the use of its SYNTAX™ System and Enzymatic DNA Synthesis (EDS) technology to generate custom oligos for SARS-CoV-2 spike protein mutagenesis. Discover how the workflow enabled rapid production and verification of optimized and variant spike protein expression plasmids, supporting recombinant protein research and synthetic biology applications.

Resource details:

Resource type: Application note
Page count: 10
Read time: 15 mins


Application NoteLife Sciences

SARS-CoV-2 amplicon sequencing

In this application note, DNA Script demonstrates the use of primers produced with its novel Enzymatic DNA Synthesis (EDS) technology for whole-genome amplicon sequencing and phylogenetic analysis of SARS-CoV-2 isolates using the ARTIC network protocol.

Explore how this technology enables decentralized, same-day, on-demand DNA oligo synthesis using a benchtop printer in a standard laboratory environment, without any specialized technical skills required.

Resource details:

Resource type: Application note
Page count: 7
Read time: 11 mins

Webinar

Optimization of a single molecule fluorescence in <i>situ</i> hybridization assay (smFISH) for Drosophila A virus detection

The use of same-day enzymatic synthesis to quickly iterate through probe design to fine-tune sensitivity and specificity has been found to accelerate the optimization of smFISH assays and thus acts as a rapid and simple alternative to immunofluorescence. In this webinar, Dr. Steven Quistad, DNA Script, and Bailey Schmidt, DNA Script, will discuss a recent study carried out in collaboration with the Institut Pasteur using on-demand enzymatic DNA synthesis (EDS) to accelerate the design-print-test-learn cycle required to optimize smFISH assays for the detection of viral RNA in the gut of Drosophila melanogaster.

Key learning objectives

  • Understand the basics of DNA synthesis (EDS) and the SYNTAX System
  • Understand how on-demand EDS probes printed on the SYNTAX System accelerates smFISH assay optimization
  • Understand how generating labeled probes with the SYNTAX System accelerates iteration
  • Discover the advantages of making on-demand DNA with enzymes

Who should attend?

  • Gene expression researchers
  • Genomics researchers
  • Anyone who performs FISH or smFISH assays
  • Anybody who has ever waited on DNA to arrive to start an experiment

Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.







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DNA biomanufacturing platform which turns any digital sequences into GMP-grade DNA

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