Sunscreen
The primo LNP formulation screener
Receive your quote directly from the manufacturer.
Very reproducible results, versatile and reliable!
Non-Viral Delivery
Time saving, process development efficiency and great customer service. Nothing similar out there in the market.
Review Date: 16 Jan 2024 | Unchained Labs
Great results
LNP formulation
Very easy to use compared to doing manually, after-sales care alright thus far, great value for money and time.
Review Date: 16 Jan 2024 | Unchained Labs
Good results to enjoy
Body
Excellent product to use. Good purchase with after sales service
Review Date: 16 Jan 2024 | Unchained Labs
Crank them out
Finding the perfect LNP formulation can feel like it drags on forever. You need to figure out the best lipid mixture, the right lipid to payload ratio and the optimal flow rates to mix it all together. Worst of all, it’s usually done one experiment at a time. Sunscreen totally flips the script by creating 96 unique, small volume LNP formulations in less than 6 hours – so you can explore more formulations in a single day than you ever thought was possible. Get brochure.
- 96 formulations in <6 hours
- 200 μL – 2 mL per experiment
- 0.1 – 30 mL/min flow rates
- Reusable microfluidics
- Scalable method
Brochures
Sunscreen
In this product brochure, Unchained Labs introduces Sunscreen, a tool designed to expedite lipid nanoparticle (LNP) formulation processes. Sunscreen streamlines the traditionally time-consuming task of finding the ideal lipid mixture and ratio by generating 96 distinct, small-volume LNP formulations within just six hours. This innovative approach enables researchers to explore a vast array of formulations in a single day, greatly enhancing efficiency and accelerating the development process.
Accelerate your LNP formulation screening with Sunscreen’s automated microfluidic technology
In this application note, Unchained Labs introduces a high-throughput screening solution, Sunscreen, designed to accelerate the formulation screening process for lipid nanoparticles (LNPs). LNPs are pivotal in the clinical delivery of nucleic acids and hold immense potential for rapid translation from concept to clinic, as evidenced by the swift development of COVID-19 vaccines like Spikevax® (Moderna®). Despite their effectiveness, LNPs are complex, requiring careful selection of specific lipids and precise ratios for successful RNA binding and delivery. With over 18 LNP-based products currently in clinical trials, the field is rapidly evolving, incorporating diverse materials and complex components, including passive and active targeting strategies for specific organ and cell type delivery. Sunscreen streamlines this intricate formulation process, enabling 96 automated experiments in under six hours, thereby boosting efficiency and paving the way for future discoveries in drug development.
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