ScriptGuard™ RNase Inhibitor
Inhibits eukaryotic RNases A, B and C. Use as a safeguard against RNA degradation in any RNA-containing reaction.
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ScriptGuard™ RNase Inhibitor prevents the degradation of RNA by eukaryotic RNase A, RNase B and RNase C, but it does not inhibit RNase 1, RNase H, RNase T1, RNase T2 or S1 Nuclease. A potent affinity for RNases, with Ki ~10-14 M, and a 1:1 binding ratio ensures rapid inhibition even when trace amounts of RNase are present. ScriptGuard™ RNase Inhibitor is free of detectable RNase and DNase activities and mammalian DNA. Because it does not interfere with most commonly used enzymes, it can be used widely, including in cDNA synthesis, in vitro transcription and translation reactions. Product is for research use only (RUO).
