ScriptCap™ Cap 1 Capping System
Build Cap 0 or Cap 1 caps with nearly 100% efficiency. Provides all reagents for capping in vitro transcribed RNA.
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The ScriptCap™ Cap 1 Capping System provides both the CELLSCRIPT™ ScriptCap™ Capping Enzyme and ScriptCap™ 2'-O-Methyltransferase allowing the user to produce either a Cap 0 or Cap 1 cap structure at approximatey 100% efficiency on the 5' end of in vitro transcribed RNA. ScriptCap™ Capping Enzyme catalyzes in vitro addition of a cap nucleotide to the 5' terminus of primary RNA that has a 5'-triphosphate group. A "cap nucleotide" or “cap” is a guanine nucleoside that is joined via its 5' carbon to a triphosphate group that is, in turn, joined to the 5' carbon of the most 5' nucleotide of the primary mRNA transcript, and in most eukaryotes, the nitrogen at the 7 position of the guanine in the cap nucleotide is methylated. Product is for research use only (RUO).
