Prep 150 LC System
The Prep 150 LC System is a fit for purpose solution designed for scientists requiring robust system performance with intuitive software for dedicated personal purification or quick adoption in centralized labs. Systems are designed to satisfy your application requirements, whether you are processing a few samples a day, or your workload demands greater through-put with unattended automation. The Prep 150 LC System allows you…

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The Prep 150 LC System is a fit for purpose solution designed for scientists requiring robust system performance with intuitive software for dedicated personal purification or quick adoption in centralized labs. Systems are designed to satisfy your application requirements, whether you are processing a few samples a day, or your workload demands greater through-put with unattended automation. The Prep 150 LC System allows you to rapidly process your valuable complex mixtures resulting in high-purity and recovery with complete confidence.
Features of the Prep 150 LC System:
- Flexible solvent delivery options allowing binary or quaternary based pumps providing low-pressure multi-solvent blending or high pressure gradient mixing of flow rates up to 150 ml/min.
- Easy to use manual or automated sample injection options allow the versatility to accommodate a wide range of workload requirements.
- Identify and isolate your compounds of interest with the highly sensitive 2489 UV/Visible or 2998 Photodiode Array detectors, providing enhanced linear range to accommodate highly concentrated samples.
- Confidently purify sample loads of milligrams to grams when using internal column diameters of up to 50mm.
- Use the easy-to-navigate ChromScope software delivered with sample set wizard, stacked injection wizard, key fraction collection parameters, fraction simulation modeling, and customizable reporting with drop and drag features.
Considerations for Analytical to Preparative Scaling
Developing separation methods on a small scale and transferring them to a larger scale can help a lab reduce its consumption of sample and solvents. Using the appropriate factors scientists can scale up from analytical chromatography to larger scale preparative separations. In this application note the Prep 150 LC System from Waters, a system for preparative chromatography, is used with egg white to demonstrate transference from a 4.6mm ID analytical column to a 19mm ID preparatory column separation.
Purification of Cannabidiol from Hemp Oil Using the Prep150 LC System
Cannabidiol (CBD) is thought to have a wide scope of potential medicinal benefits. Following extraction from hemp, purification or isolation of the compound is required to provide sufficient amounts of a high-purity compound for use in bioassays. This application note describes the purification of CBD from a CBD-rich paste using the Waters® Prep 150 LC System.
Isolation of a Natural Product from Echinacea Extract Using the Prep 150 LC
One of the major compounds in Echinacea purpurea flowers is cichoric acid, a phenylpropanoid and a caffeic acid derivative. This application note focuses on the feasibility of using the Prep 150 LC System as a tool for isolating cichoric acid from Echinacea purpurea extract.
















