OsmoTECH® Single-Sample Micro-Osmometer
Designed specifically to meet the demanding needs of the biotech industry
Reliable without constant calibration
Check osmolarity of solution buffers
So far, the OsmoTECH has produced reliable results without needing constant calibration. Purchasing was straightforward, and the sales team was willing to work with us so we could get exactly what we needed.
Review Date: 10 Apr 2024 | Nova Biomedical (with Advanced Instruments)
Great equipment
Cells
Great equipment
Review Date: 24 Sept 2022 | Nova Biomedical (with Advanced Instruments)
Excellent results with high reproducibility
Osmolality testing of drug substance and drug product and for formulation development of biological
It is highly effective and obtained results are of high quality. With this instrument I can develop my formulation for meeting the osmolality criteria for drug products
Review Date: 12 Jul 2022 | Nova Biomedical (with Advanced Instruments)
Simple, reliable, easy to operate
Osmolarity evaluation in media and cell culture
It was quite easy to use, instructions were simple. Easy calibration methods. Reliable results and training other people was easy.
Review Date: 11 Jul 2022 | Nova Biomedical (with Advanced Instruments)
Great and easy to use
Tissue culture buffers and media
Easy to use and fast readings.
Review Date: 28 Mar 2022 | Nova Biomedical (with Advanced Instruments)
Great reproducible results
Osmometric test of oral solutions
Testing is quick , easy & reproducible. The results are reliable and the standardization is also easy.
Review Date: 25 Mar 2022 | Nova Biomedical (with Advanced Instruments)
Great accurate results with 21 CFR compliance.
Analysis of finished product osmolality
The best part of the instrument is it gives accurate and reproducible results for any solution and most importantly in less than a minute you have the results.
Review Date: 19 Mar 2021 | Nova Biomedical (with Advanced Instruments)
Great instrument and good value for money.
Measurement of the contribution of various solutes present in the product against osmosis
Achieves high quality and reproducible results. Easy instrument to use and well presented software. After care sales team were so helpful with any requests we had about the instrument and with making sure we were happy with the quality of the equipment and services we received.
Review Date: 12 Jun 2020 | Nova Biomedical (with Advanced Instruments)
Great piece of kit.
Pharmacopoeial osmolality testing
Easy to use and robust piece of equipment that met all our user and regulatory requirements. The hardware is sleek, efficient and easy to use. The integrated software has built in data integrity controls and is thoroughly tested through validation test scripts / reports. The Advanced Instruments team were extremely helpful and receptive to our requirements - highly recommend you talk to them if you require an osmometer.
Review Date: 30 Jan 2020 | Nova Biomedical (with Advanced Instruments)
Manufacturer's Response
Thank you for your positive review! We’re so glad to hear that you are happy with your instrument. It’s the feedback from customers like you that help us innovate and continue to be the leading industry experts in osmometers. If you have any recommendations or additional feedback, we’d love to hear from you! Please send us an email to info@aicompanies.com or give us a call at 781-320-9000.
Great instrument with easy operation
Sample analysis and verifictaion
Product is worth it. It is super easy to use and gives consistent results.
Review Date: 3 Dec 2019 | Nova Biomedical (with Advanced Instruments)
Manufacturer's Response
Thank you for your positive review! We’re so glad to hear that you are happy with your instrument. It’s the feedback from customers like you that help us innovate and continue to be the leading industry experts in osmometers. If you have any recommendations or additional feedback, we’d love to hear from you! Please send us an email to info@aicompanies.com or give us a call at 781-320-9000.
OsmoTECH is designed to meet the needs of the biotech industry. The easy-to-use system is designed to be intuitive, reliable and flexible for those who prefer to directly draw and test small sample volumes. Its flexible data management features, and its gold-standard testing method uses freezing point depression to provide the accuracy and precision you need to optimize your process and quality control program.
Features:
- Intuitive touchscreen - Easy-to-use with an intuitive, color-coded menu-driven operating system, with multi-language capability.
- Connectivity - The OsmoTECH provides secure data transfer to LIS and data management systems via Ethernet connection.
- Industry leading accuracy and precision - OsmoTECH utilizes the industry-preferred freezing point depression method to accurately and precisely determine osmolality.
- Meets osmolality testing guidelines as described by Pharmacopeias ( USP, EP, JP and CP).
Brochures
OsmoTECH Single-Sample Micro-Osmometer
Osmolality testing is a robust in-process control and quality check you can implement through process development to ensure optimum media preparation, cell health, and product quality and yield. OsmoTECH's data management features support 21 CFR Part 11 Compliance, amd its gold-standard testing method uses freezing point depression to provide the accuracy and precision you need to optimize your process and quality control program.
Osmolality as a valuable tool in formulation studies for advanced therapies
Whilst osmolality is a compendial QC test for final product release, it’s also useful in formulation development and stability studies for drug products. It provides the excipient concentration and can confirm the soluble content of formulations. In this scientific poster, the rapidly advancing field of cell therapy is discussed, where cryoprotective storage strategies are common.
Osmolality as a predictor for protein purification
The bottleneck for real-time control and real-time release is lack of product specific in-line sensors or fast at-line methods suitable for model based prediction of process outcome. In this poster, the question whether or not osmolality can be used as an additional predictor for protein purification is addressed.
Osmolality as a Concentration Measurement Method for Key Buffers in Bioprocessing
The manufacturing of biologics is a complex and costly process by which a protein is recovered and purified of contaminants to ultimately generate a drug product. This is accomplished through a chain of filtration and chromatography processes. Achieving and maintaining the desired product quality and purity requires optimization of process parameters as well as precise control of these parameters.
Osmometry: Supporting your product throughout development and manufacturing
Osmolality testing is an in-process control and quality check that is used throughpout the development and manufacture of biologics. Find out more about the portfolio of products available from Advanced Instruments designed to meet your biotech osmolality needs.
OsmoTECH Single-Sample Osmometer: Built for biotech
In this video, experience a new level of bioprocess control with the OsmoTECH Single-Sample Osmometer from Advanced Instruments, a critical step to ensure batch yield and quality.



























