ON-TARGETplus Human siRNA
siRNA designed and modified for greater specificity
Gene silencing guaranteed. Patented modifications to reduce off-targets; individual or SMARTpool format pre-designed ON-TARGETplus siRNA available
- Off-targets reduced by up to 90% compared to unmodified siRNA
- Guaranteed silencing by SMARTpool and 3 of 4 individual siRNAs (see Guarantee tab)
- Sequence information provided with siRNA purchase
Reducing off-target effects in RNA interference experiments
In this article, Dr. Christian Nievera, senior product manager at Horizon Discovery, discusses how to minimize non-specific effects of siRNA reagents








