Products & ReviewLife Sciences
OAC1
Inducer of OCT4 expression
OAC1
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OAC1 is an OCT-4-activating compound that activates expression through the OCT-4 gene promoter (Li et al.). Oct-4 (POU5F1) is a transcription factor that is critically involved in the self-renewal of pluripotent stem cells, and its expression is commonly used as a marker for pluripotency.
REPROGRAMMING
- Enhances the reprogramming efficiency of mouse embryonic fibroblasts transfected with OCT4, SOX2, KLF4, and c-MYC (Li et al.).
MAINTENANCE AND SELF-RENEWAL
- Mediates ex vivo expansion of cord blood CD34+ hematopoietic stem and progenitor cells (Huang et al.).
