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Morphologi 4-ID

Rapid, automated, component-specific particle characterization in a single, integrated platform

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Malvern Panalytical

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Average Rating 5.0

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An unique instrument to probe complex drug product.


Average Rating 5.0

Application Area:

Simultaneous physical and chemical analysis (Q3 microstructural understanding)

It is a very compact and handy system to use and operate. It offers simultaneous physical and chemical analysis to probe complex drug formulations effectively. It is a useful system for drug product development as regulatory product guidance demands synchronized morphological and chemical fingerprinting. Briefly, it is a useful system for quick and reliable analysis.

Review Date: 6 Sept 2022 | Malvern Panalytical

Morphologi 4-ID delivers detailed component-specific morphological descriptions of particulate blends through Morphologically-Directed Raman Spectroscopy (MDRS). This combines automated particle imaging with Raman spectroscopy in a single, integrated platform, providing the power to unlock complex particle characterization problems.

  • Patented MDRS capability delivers representative component-specific particle size and shape data, delivering full characterization of your sample
  • All the functionality of the Morphologi 4 combined with a dedicated Raman platform for both physical and chemical particle characterization in a single, automated measurement
  • Automatically measures Raman spectra for hundreds or thousands of particles, saving valuable analyst time
  • Intuitive software ensures suitability for experienced and non-experienced spectroscopists alike
  • Easy correlation of morphological properties with chemical information provides the most comprehensive understanding of your sample
  • 21 CFR Part 11 software option ensures regulatory compliance
  • Adaptable workflows enable methods to be tailored to specific user or application requirements. Select particles for chemical analysis:
    • manually, from particle images
    • morphologically-directed, based on user-specified classifications (MDRS)
    • automatically and objectively by the software
  • Ability to export spectra in industry-standard format supports unknown component identification using 3rd party spectral libraries
  • Tight control of laser power and acquisition time enables measurement optimization for a wide range of materials, from weak Raman scatterers to those that are thermally sensitive

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