Products & ReviewLife Sciences
Line-1 Methylation Assay
EpigenDxAvailable: Worldwide
LINE repetitive element methylation assays for human, mouse, rat, or monkey.
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Description
Global DNA methylation assays using LINE elements (long disperse elements) as a markers.
Application NoteLife Sciences
LINE-1 global methylation analysis
As LINE-1 constitutes approximately 17% of the human genome, the extent of LINE-1 methylation is regarded as a surrogate marker of global DNA methylation.
In this application note, EpigenDx demonstrate the use of LINE-1 methylation levels as an excellent pharmacodynamic (PD) marker for hypomethylating agent therapy.
