Invitrogen™ TrueDesign™ Genome Editor
Free online tool enables researchers to easily design, select, and order reagents for precise gene editing experiments
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Great
Biopharma
Overall good, we got good support from service
Review Date: 25 Mar 2022 | Thermo Fisher Scientific
Easily create accurate and more successful gene editing experiments with TrueDesign Genome Editor. The free design tool has an intuitive point-and-type interface that provides unrivaled flexibility and support for creating genome edits. It supports gene knockout, fluorescent tagging, epitope tagging, insertion, replacement, deletion, and SNP creation in five different species. Once designed, you can add all necessary gene editing reagents to your cart with a single click, including our trusted TrueCut™ Cas9 proteins, TrueGuide™ synthetic gRNAs, and TrueTag™ Donor DNA Kits. Design your next genome editing experiment like an expert, all in as few as 5 minutes.
Tips and tricks for CRISPR-Cas9 success
In this infographic, Thermo Fisher Scientific discusses some CRISPR-Cas9 best practises to help you optimize your gene editing workflows.
Key considerations in genome editing
CRISPR gene editing has emerged as one of humanity’s most powerful technologies. Less expensive and relatively easy to design and use compared with older technologies such as zinc finger nucleases, CRISPR-Cas9 approaches are transforming biomedical science. Used initially as a tool to study gene function, the next generation of CRISPR-Cas9 tools are now allowing researchers to target almost any gene for modification in a highly specific and reliable way.
In this eBook, we take a look at the innovative suite of CRISPR-based editing tools from Thermo Fisher Scientific, how those tools can support both basic and applied research applications, and how these tools can be used to improve fidelity and efficiency along every stage of a gene editing workflow – from guide RNA (gRNA) design to cell transfection and characterization of successful edits.
Download for expert advice including how to:
- Design your genome editing experiments with ease
- Achieve high editing efficiency
- Leverage CRISPR for target identification
- Seamlessly translate your research from bench to clinic
Genome editing resource guide
Download this application note from Thermo Fisher Scientific to discover a complete toolset of trusted solutions for every step in the cell engineering workflow.
A step-by-step workflow for a PDCD1 knock-out experiment in T cells
This step-by-step tutorial video demonstrates the process of conducting a PDCD1 gene knock-out in T cells using the Neon™ NxT Electroporation System. See how to design the experiment using the Invitrogen™ TrueDesign™ Genome Editor software; prepare both cells and reagents; conduct post-transfection assessment; and validate the success of the PDCD1 knock-out for further experimentation. For additional support designing CRISPR gene editing experiments, visit thermofisher.com/geneediting or explore the other tutorial videos in this series:
7 innovations in gene editing technology
Discover the latest webinars, methods and products in gene editing technology
Explore the role of CRISPR gene editing in target validation
Learn how researchers are using innovative gene editing techniques to uncover new drug targets
Collaboration and CRISPR tools move scientists closer to a cure for sight loss
See how researchers are uncovering the mechanisms of retinal degeneration and identifying new targets for therapeutic intervention
Modeling rare diseases using CRISPR gene editing – Could fruit flies save lives?
How alternative animal models are helping scientists uncover the genes responsible for rare and ultra-rare diseases
Design your CRISPR gene editing experiments in as little as five minutes
Discover how the suite of gene editing technologies from Thermo Fisher Scientific is simplifying gRNA and experimental design
Overcoming the challenges in your gene editing workflow
Learn how Thermo Fisher Scientific can support your gene editing research
Meet your winners in the 2022 Scientists’ Choice Awards for Life Sciences
Beckman Coulter Life Sciences, Zymo Research, and Corning Life Sciences among those recognized at AACR 2022
