FormaPure Total
Total Nucleic Acid Isolation from FFPE Tissue
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High-quality results.
Isolating DNA and RNA
This kit is the best I never tried for isolating both RNA and DNA from FFPE samples. I strongly recommend it because of the high-quality results. The protocol is very easy, and it allow you to isolate DNA and RNA from an unique sample, which is really convenient sometimes.
Review Date: 25 Jul 2018 | Beckman Coulter Life Sciences
Maximizing sample integrity, yield and purity from FFPE samples is required to minimize the risk of losing critical genetic information. FormaPure Total isolates both RNA and DNA from often challenging formalin-fixed, paraffin-embedded (FFPE) tissue, and provide researchers flexible, scalable solutions that generate consistent results while maintaining higher integrity nucleic acids to support the improved sensitivity of next-generation sequencing (NGS) applications.
FormaPure Total is one of three reagent kits in the FormaPure family, which also includes FormaPure DNA for DNA isolation and FormaPure RNA for RNA isolation. FormaPure reagent kits are a single chemistry system designed and optimized for use in NGS and other downstream applications including qPCR/ddPCR/PCR.
Brochures
FormaPure Reagent Kits
Manual or Automated RNA, DNA or Total Nucleic Acid Extraction from FFPE
From Genes to Discovery: How Next-Generation Sequencing Reshapes Cancer Research
Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020.1 Prostate cancer ranks as the second-leading cause of cancer-related deaths among American men, surpassed only by lung cancer.2
Join our upcoming webinar featuring Dr. Nallasivam Palanisamy, Henry Ford Health and Zachary Herbert, Dana-Farber Cancer Institute, as they delve into the rapidly escalating role of next-generation sequencing (NGS) in revolutionizing cancer research.
The speakers will examine the pivotal significance of NGS technology in unraveling intricate cancer mysteries. With a focus on prostate cancer, the webinar will highlight transcriptomic signature – a ground-breaking approach to illuminate the genetic nuances underlying cancer disparities, particularly in African American men. The transformative power of transcriptomic analysis will be demonstrated along with insights into the latest advancements and their implication for cancer treatment.
Furthermore, how the automation revolution is reshaping the landscape of cancer research will also be explored. Through pioneering automation techniques, researchers can now manage testing volumes and reduce turnaround times, accelerating the pace of discovery. This innovative approach will be showcased through pilot data displaying the successful application of RNAse1/hybrid capture in a current project.
Dr. Nallasivam Palanisamy is an associate Scientist in the Department of Urology at Henry Ford Health. Palanisamy specializes in prostate cancer, cancer genomics, and molecular cytogenetics/molecular pathology. His research interests are on discovering and characterizing gene fusions in cancer and understanding their role in carcinogenesis from a translational research perspective.
Zachary Herbert is the Director of the Molecular Biology Core Facilities, Lead Scientist at Dana-Farber Cancer Institute, and an Associate Director of the Harvard University Center for AIDS Research Advanced Laboratory Technologies Core. His laboratory primarily focuses on developing and implementing NGS sample preparation, sequencing, and bioinformatics services to advance basic and translational research. He has a BA in Molecular Biology and Biochemistry, a Master’s in Biotechnology, and 20 years of experience running a high-throughput genomics facility.
Ferlay J, Ervik M, Lam F, Colombet M, Mery L, Piñeros M, et al. Global Cancer Observatory: Cancer Today. Lyon: International Agency for Research on Cancer; 2020. Available from URL: https://gco.iarc.fr/today?
American Cancer Society.?Facts & Figures 2023. American Cancer Society. Atlanta, Ga. 2023. Available from URL: https://www.cancer.org/cancer/types/prostate-cancer/about/key-statistics.html??
Key learning objectives
- Explore effective FFPE RNA utilization in NGS for cancer research
- Learn more about the identification of key genes driving aggressive prostate cancer in African Americans, aiding racial disparity workflow understanding
- Discover NGS workflow automation’s role in accelerating tumor biology insights
Who should attend?
- Academia
- Government research
- Contract research organic
- Hospitals
- Clinical
- Pharma
- Biotechnology
- Medical centers
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
