Edit-R synthetic sgRNA libraries
Simplify CRISPR editing in all cell types including primary cells with Edit-R synthetic sgRNA libraries
Further your functional genomics studies with CRISPR-Cas9 gene editing using Edit-R™ synthetic sgRNA libraries. Analyze hundreds of genes with multiple target sites per gene. Collections include whole genome, human druggable genome, and common gene family libraries.
Arrayed library format permits single-well analysis with many phenotypic assays; including high-content assays and other morphological or reporter assays.
Highlights of Edit-R™ synthetic sgRNA libraries:
- Selected by the Edit-R™ algorithm. Highly functional and specific target sequences for robust, reliable gene knockout. Chemically modified for improved nuclease resistance
- For high-confidence phenotypic results, provided as three unique sgRNA designs per gene, as a pooled reagent
- Conveniently arrayed in 96-or 384-well plates and offered as gene family collections. Echo-qualified 384-well plates are available upon request
- Also available as sgRNA cherry-pick libraries; simply upload your own gene list and customize your plate
- Human Druggable is made up of: Proteases, Protein Kinases, Phosphatases, Transcription Factors, Ubiquitin Enzymes, GPCRs, Ion Channels and Drug Targets.
Manipulating iPSCs with CRISPR – Functional knockouts, fluorescent tagging, and expression activation
This application note by Horizon Discovery presents the ability to modify the genome and modulate expression of genes within a human induced pluripotent stem (iPS) cell line with Dharmacon™ Edit-R CRISPR reagents.
Dharmacon gene editing workflows
This workflow guide by Horizon Discovery will assist you in selecting the right Edit-R™ genome engineering tools for your application.
Dharmacon siRNA selection guide
Horizon Discovery offer a wide selection of pre-designed siRNA product lines and formats. This quick selection guide will help to determine the best option for your particular needs.
Validate your target hits: Use cell-based screening services
This brochure aims to teach you how to validate your target hits by using cell-based screening services.
CRISPR gene editing: Edit with confidence
This brochure by Horizon Discovery aims to help you maximize knockouts, minimize off-target effects with Edit-R™ reagents.
Gene modulation by Dharmacon: Focus on function
Keep gene modulation simple with predesigned reagents by Dharmacon.








