Chromium Single Cell Epi ATAC
Next GEM Epi ATAC Chromatin organization compacts meters of DNA into the nucleus, making just a small fraction of DNA accessible for transcription within each cell.

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Excellent product
Single-cell sequencing technology
Great product that provided gene expression and chromatin accessibility data from single cells with ease
Review Date: 24 Mar 2022 | 10x Genomics
The Next GEM Epi ATAC (Assay for Transposase Accessible Chromatin) solution provides a robust and scalable approach to map the epigenetic landscape at single cell resolution. Using a transposase enzyme to preferentially tag accessible DNA regions with sequencing adaptors, researchers can now generate sequencing-ready libraries and identify open chromatin regions.
Our simple workflow, combined with intuitive software, enables understanding of epigenetic and regulatory variation across tens of thousands of cells.
- Resolve cell types and states using genome-wide, epigenetic profiles with single cell resolution
- Discover cis-regulatory elements that drive gene expression differences between cell types and states
- Characterize cell-specific gene regulatory networks to understand the epigenetic underpinnings of disease, developmental plasticity, and cell identity
- Identify transcription factors (TFs) that determine cell identity, and perform lineage and developmental tracing
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