BRANDplates® Insert System for 3D Cell Culture

Innovative cell culture plates and inserts for co-culture, migration/invasion assays, 3D tissue preparation and more.

The BRANDplates Insert System, co-developed with the Fraunhofer Society, offers an innovative expansion of the BRAND cell culture product line. The new Insert system consists of 24-well standard and 6-well specialized plates and strips of hanging cell culture inserts for applications such as co-culture, migration/invasion assays, or the automated in vitro preparation of human tissues (3D cell culture).

Unique features such as insert guide grooves and side feeding ports ensure insert stability and prevent tissue or cell disruption during media changes, especially with pipetting robots. Furthermore, the inserts may be smooth walled or feature inlet channels (inlet opening system) to increase the ease of media change for long term cell or tissue culture.

The polystyrene (PS) plates are sterile, and untreated or cell culture treated dependent upon application. The insert strips consist of 4 wells per strip and the membrane may be polycarbonate (PC) or polyethylene terephthalate (PET) for different imaging requirements. The pore sizes of the membranes are available in multiple pore sizes (0.4 µm, 1 µm, 3 µm, 8 µm) to allow for the movement or inhibition of molecules of varying sizes. Altogether the components of the new Insert System can be configured for highly customized uses ensuring an efficient solution for manual and automated cell and tissue culture work.

Features:

• 24-well standard and 6-well specialized multiwell sterile plates, untreated or cell culture surface
• 4 place strips of divisible inserts with PC or PET membranes and 4 pore sizes (0.4 µm, 1 µm, 3 µm, 8 µm)
• Hanging inserts with guide grooves to ensure insert stability
• Unique side feeding ports to allow changing of media without disturbing cells or tissue
• Available with or without side channels (inlet opening system) for rapid and consistent media changes
• Lids with condensation rings to prevent well contamination
• Manufactured according to ANSI/SLAS Standards 1 and 4
• Sterile according to ISO 11137 and AAMI Guidelines, SAL 10-6
• Non-cytotoxic according to ISO 10993-5, endotoxins free (<0.01EU/mL)
• Free from DNA, DNase, and RNase

Applications:

• 3D Tissue Culture
• Co-Culture
• Migration/Invasion Assays
• Chemotaxis Assays