BIOne Single-Use Bioreactor System
The BIOne benchtop scale single-use bioreactor (SUB) is for mammalian cell growth, cell therapy, insect cells, and other unique applications performed in a stirred tank bioreactor. The gamma irradiated BIOne SUB is engineered with a disposable headplate welded to a triple-layered liner that can be easily inserted into a non-sterile bioreactor glass vessel, converting it to a disposable SUB within a matter of seconds.
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The BIOne benchtop scale single-use bioreactor (SUB) is for mammalian cell growth, cell therapy, insect cells, and other unique applications performed in a stirred tank bioreactor. The gamma irradiated BIOne SUB is engineered with a disposable headplate welded to a triple-layered liner that can be easily inserted into a non-sterile bioreactor glass vessel, converting it to a disposable SUB within a matter of seconds. Upon media addition, the liner expands and molds to the glass vessel, preserving the geometry of the existing bioreactor.
The BIOne SUB’s liner material emulates the large-scale SUBs used in pilot and commercial biopharma production facilities around the world. Performing R & D studies using the most similar material on the market streamlines your tech transfer and can de-risk your process BEFORE transferring to pilot scale.
CUSTOMIZABLE ABOVE & BELOW THE HEADPLATE
- 2L & 5L Working Volume
- Optional Single-Use pH Probe
- Increased Throughput
- Weldable Tubing
- Flute, Micro & Open Pipe Sparging Options
- Non-Invasive DO & Optional pH Probe Ports
- USP Class VI Materials
- Repligen® ATF Perfusion Tube Compatible
- Animal Derivative-Free
- Low Antioxidant Liner Material
- Compatible with Most Manufacturers’ Glass Vessels and Controllers
DO & pH PROBE PORTS
- Non-Invasive (Amperometric DO/Optical pH)
- PG-13.5 (Optical DO/Electrochemical pH)
- Optional Integrated Single-Use pH Probe
PITCHED BLADE IMPELLER
- Single or Dual Impeller
SPARGING OPTIONS
- Flute Sparger (7 x 1.5 mm hole)
- Micro Sparger (20-40 μm pore size)
- Open Pipe Sparger (1 x 3.0 mm)
LOW ANTIOXIDANT LINER MATERIAL
- Outer Layer (LDPE) – Mechanical Strength
- Middle Barrier Layer (EVOH) – Gas Barrier
- Contact Layer (ULDPE) – Cell Culture Compatible, Biologically Inert
BIOne Benchtop Solutions
In this video, Distek introduces the BIOne 1250 Bioprocessing Controllers, capable of supporting both cell culture and fermentation processes.
Distek partners with Optimal Biotech Group to expand BIOne Bioreactor Solutions on the West Coast
Optimal Biotech Group will represent Distek’s BIOne portfolio, including the BIOne 250 and BIOne 1250 Bioreactor Controllers, as well as BIOne Single-Use Bioreactors and Fermentors
