Anti-Mouse IgG Fc (MFC) XT Probes

Gator^® Anti-Mouse IgG Fc (MFC) XT Probes are next generation anti-mouse IgG Fc capture biosensors engineered for superior performance and broad dynamic range. They support both quantitation and kinetic analysis of mouse IgG antibodies and mouse Fc-fusion proteins. The MFC XT biosensors exhibit high affinity for all four mouse IgG subclasses (IgG1, IgG2a, IgG2b, IgG3) with minimal cross-reactivity to rat, human, and bovine IgG. They are suitable for measuring mouse IgG in both crude and purified samples. With up to a 4-fold increase in ligand binding capacity, the sensors provide enhanced kinetic characterization of small proteins and enable detection of low-abundance mouse antibodies in hybridoma cultures. MFC XT biosensors can be regenerated up to 20 times with minimal loss of performance, delivering a cost-effective solution for high-throughput applications in lead screening, selection and cell line development.