Anti-His (HIS) XT Probes
High-performance His-tagged protein capture for rapid quantitation, kinetic measurements and epitope binning
The supplier does not provide quotations for this product through SelectScience. You can search for similar products in our Product Directory.
Gator HIS XT Probes are the first to incorporate a novel AI-designed anti His NovoBody™ (designed by Monod Bio) as a ready-to-use probe, delivering next-generation bilayer interferometry (BLI) performance for His-tagged protein analysis. This probe is engineered to enable industry-leading high affinity specific poly-His capture with far greater capture half-life, providing a robust platform for real-time quantitation or kinetic analysis and epitope binning with interacting analytes.
The HIS XT Probe capture surface exhibits high affinity and specificity toward both N- and C-terminal His-tags, ensuring stable ligand capture with 58% less baseline drift compared to other anti-His capture systems. With an advanced optical design, HIS XT delivers up to 4-fold higher response per captured protein along with low non-specific binding. Together, HIS XT enables reliable measurements for analytes with pM - µM affinities in complex media, inclusive of small analytes (<15 kDa). Its high dynamic range enables optimized avidity control and flexibility as well as simplified quantitation workflows.
HIS XT probe for advanced His-tag capture for kinetics, quantitation and epitope binning
This application note describes the performance and utility of the Gator Bio Anti‑His (HIS) XT Probe, a next‑generation biolayer interferometry (BLI) biosensor designed for high‑resolution analysis of His‑tagged proteins. Using an AI‑designed NovoBody™ capture ligand and advanced optical coating, discover how the HIS‑XT probe enables reliable kinetics, quantitation, and epitope binning with improved baseline stability, reduced sample consumption, and robust regeneration across diverse protein targets.
