Accel-NGS® Methyl-Seq DNA Library Kit (96 reactions)
Providing ultimate coverage of methylated DNA.
Accel-NGS® Methyl-Seq DNA Library Kit
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Maximizes DNA recovery of bisulfite-converted samples and constructs libraries that accurately represent sample base composition.
Supported applications include:
- WGBS (Whole Genome Bisulfite Sequencing).
- RRBS (Reduced Representation Bisulfite Sequencing).
- Enrichment of bisulfite converted DNA: MeDIP, ChIP, oxBS.
- Hybridization capture: NimbleGen SeqCap Epi Enrichment, MeCAP.
- Ancient DNA samples that may contain uracil nucleotides as a result of damage.
The right choice when performing methylation sequencing to yield the greatest amount of data across a variety of sample types.
NGS Library Preparation Produces Balanced, Comprehensive Methylome Coverage from Low Input Quantities
Next-generation sequencing (NGS) of bisulfite-converted DNA to detect methylation status with per-base resolution is currently restricted by input requirements, requiring at least 50 ng of DNA. This Application Note shows how the unique chemistry of the Accel-NGS® Methyl-Seq DNA Library Kit enables the construction of high complexity
libraries.
A Guide to NGS Applications Using cfDNA Samples
This guide from Swift Biosciences provides an introduction to using cell-free DNA to construct NGS libraries for use in cancer research. The guide compares the range of kits available, how well they perform and their limitations.
