6530 Q-TOF LC/MS
Raise your analysis to a new level with the Agilent 6530 Quadrupole Time-of-Flight LC/MS system. The 6530 delivers the power of high-resolution, accurate-mass MS/MS, so you can be fully confident of your data.
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Proteomics
It enables high quality results because it can get very accurate mass. With chip cub, it is easy to use. But the chip is very expensive and it is easy to break. Service is very good, on time. So value for the money is medium.
Review Date: 9 Nov 2015 | Agilent Technologies
It is a high resolution mass spectrometer. The MassHunter software is an easy to use program. The mass accuracy is below 1ppm, the resolution is high enough.
Review Date: 27 Aug 2013 | Agilent Technologies
Pharmacokinetics
It is a very well made, robust machine. It's the most sensitive LCMS that I have used for large molecule identification. Maintenance and daily calibrations are easy. Single samples are easy however data analysis for single sets are cumbersome.
Review Date: 16 Feb 2012 | Agilent Technologies
The software offers several features which can make it difficult to follow.
Review Date: 31 Aug 2011 | Agilent Technologies
Good for HPLC/MS.
Review Date: 5 Aug 2011 | Agilent Technologies
Raise your analysis to a new level with the Agilent 6530 Quadrupole Time-of-Flight LC/MS system. The 6530 delivers the power of high-resolution, accurate-mass MS/MS, so you can be fully confident of your data.
Features:
- Mass accuracy within 2 ppm gives you complete confidence in your analysis.
- Powerful Agilent Jet Stream source enables you to uncover low level components.
- Wide in-spectrum dynamic range facilitates simultaneous measurement of minor components in the presence of intense background interferences.
- The latest developments in Agilent Infinity II UHPLC, 2D-LC, SFC, and even GC-APCI chromatographic interfaces give you blazing fast acquisition speed.
- Powerful MassHunter software provides the latest software capabilities for profiling, characterizing, identifying, and quantifying compounds in complex mixtures via high-definition MS and MS/MS.
Evaluation of different ion-pairing reagents for LC-UV and LC-MS analysis of oligonucleotides
The effect of various ion pairing reagents (amines and acidic counterions) on the LC-UV and LC-MS analysis of oligonucleotides (ONs) has been studied. The type of amine and concentration of the counterion play a significant role in the retention and resolution of the ONs and strongly affect the MS data.
In this application note, Agilent Technologies demonstrates that there are numerous variables available for optimization of the analytical conditions for ONs. The analyses were carried out on an Agilent 1290 Infinity II LC System with UV detection by DAD and an Agilent 6530 LC/Q-TOF.
