Labcyte Launches New Family of Echo® Acoustic Liquid Handlers featuring 21 CFR Part 11 Compliance Software
State-of-the-art software supports laboratories working in regulated environments
5 Feb 2018
Labcyte Inc. has announced the release of a regulatory-ready family of Echo® Acoustic Liquid Handlers intended for pharmaceutical companies and laboratories developing and running bioassays. Integral to this new capability of Echo liquid handlers is new software, Echo® 21CFR11 Compliance Manager, and services designed to simplify deployment in regulated laboratories that must comply with the 21 CFR Part 11 regulations established by the U.S. Food and Drug Administration. Regulatory-ready versions of the Echo® 525, 550, and 555 Acoustic Liquid handlers are among several other new products the company introduced at SLAS2018 in San Diego.
Echo® 21CFR11 Compliance Manager, software included with the regulatory-ready systems, seamlessly integrates with Echo liquid handlers and Echo® software applications to control who can view, create, edit, approve, archive, and delete data that is generated by the systems. Using advanced proprietary verification algorithms, the software also detects any data tampering to give users confidence in the integrity of their data.
"The new regulatory-ready Echo® Liquid Handlers make it easier for laboratories to successfully install, qualify and operate the system in a regulated laboratory environment," said Chris Grimley, Vice President of Marketing for Labcyte. "Echo 21CFR11 Compliance Manager software prevents unwanted changes to system settings or protocols and maintains full traceability of system use, which is critical for bioassay development and implementation."
Acoustic liquid handling, pioneered by Labcyte, has been adopted across pharmaceutical sample management and screening programs for the dispensing of reagents in a wide variety of molecular and cellular assays. It uses the gentle energy of sound waves to move liquids in nanoliter increments with extremely high precision and accuracy. The technology is contactless, avoiding risks of sample carryover or cross-contamination and reduces sample volume needs, which in turn leads to improved data quality, higher throughput, and lower assay costs.
For more information about the Echo 21CFR11 Compliance Manager, including a series of tutorial workshops visit Labcyte at booth 915-921, at SLAS2018.
For more of the latest information live from SLAS 2018, visit our SLAS 2018 page
Related Products
Request Quote for All Products
Echo® 555 Liquid Handler
Beckman Coulter Life SciencesEcho® 555 liquid handler - the world's fastest acoustic dispensing platform for life science applications. The Echo® 555 liquid handler is the world’s fastest acoustic liquid handling platform for life science applications. Laboratories that demand very high throughput rely upon the Echo 555 liquid handler for round-the-clock trouble-free operation to enable the fastest discovery.The Echo 555 doubles the throughput of the Echo 550 and provides transfers from as many as 660,000 wells per day. Like the Echo 520 and Echo 550 liquid handlers, the Echo 555 uses "touchless" ADE transfer technology. ADE uses sound energy to transfer 2.5 nL droplets from Echo-qualified 384- and 1536-well source plates into 96-, 384-, 1536- and 3456-well destination plates.This unique touchless technology eliminates consumable tip costs, washing, and cross-contamination. Unsurpassed volumetric precision (≤ 8% CV) and accuracy (≤ 10% CV) ensure superior results. Independent studies have shown that Echo liquid handlers eliminate false negatives due to sample loss on tip surfaces in low-concentration transfers. Like the Echo 550 liquid handler, the Echo 555 liquid handler reports both fluid volume and DMSO hydration.Echo® 555 Liquid Handler Features: Tipless transfer, resulting in dramatic cost savings Accurate, precise movement of nanoliter-scale quantities, enabling assay miniaturization and further reducing costs Elimination of cross-contamination, carryover or leachates Better results through direct dilution of compounds, an improvement over serial dilution methods Improved information about sample integrity and improved transfer quality through measurement of DMSO hydration level Applications: Compound management Compound screening siRNA screening Biochemical assays Cell-based assays PCR Genotyping Gene expression
Echo® 650 Acoustic Liquid Handler
Beckman Coulter Life SciencesEnables assay miniaturization in a broad range of applications. Transfer from 384-well and 1536-well microplates. Accurate, precise, contact-free acoustic transfer in volumes as low as 2.5 nL Transfer from Echo Qualified sample tubes* and microplates.
Echo® 525 Liquid Handler
Beckman Coulter Life SciencesThe Echo 525 platform, like the other Echo liquid handler models, is designed to use sound energy to transfer reagents. Unlike the other Echo models, the Echo 525 platform transfers at a larger volume increment (25 nL). This enables the more rapid transfer of aqueous reagents required in biochemical and genomics assays setup.