Sensitive biophysical characterization techniques have revolutionized drug discovery. Label-free biophysical techniques like surface plasmon resonance (SPR), bio-layer interferometry (BLI), isothermal titration calorimetry (ITC), microscale thermophoresis (MST), and microfluidic diffusional sizing (MDS) are now key components in drug discovery platforms. In this eBook, we take an in-depth look at each of these biophysical methods.
“A must have instrument for drug/antibody discovery and vaccine research labs.”
SHAILENDRA KUMAR, Sterogene Bioseparations Inc
“The ITC instrument is so specific and accurate it gives in detail analysis of protein-protein interactions or protein-DNA interactions.”
Ruchir Bobde, Institute of Life Sciences
“The Red-TRIS (NTA) dye is an easy to use labeling kit for recombinant proteins with His-tag. It has high affinity and this can be easy to use in biolo...”
Chetan Chintha, NUI galway
“ITC has become my bread and butter instrument for biochemical characterization because it uses small quantities, provides precise, reproducible result...”
Katherine Hoffmann, California Lutheran University
“The dream instrument for protein characterization, we can't be without it in the lab!”
Kevin Balcaen, VIB Protein Core
“Easy to use, speedy, and robust.”
Sankalp Gupta, Sanofi