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Thermo Fisher Scientific Signs Distribution Agreement with MKI for Lipidomics Software

Thermo Fisher Scientific
8 Jul 2013

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Thermo Fisher Scientific Inc., has signed an agreement with Mitsui Knowledge Industry Co., Ltd. (MKI) of Tokyo to become the exclusive worldwide marketer and distributor of MKI’s Lipid Search software for interpretation of lipidomic research data.

Lipid Search software, developed by Prof. Ryo Taguchi of The University of Tokyo and MKI, supports Thermo Scientific high-resolution accurate-mass Orbitrap and hybrid Orbitrap systems as well as triple quadrupole mass spectrometers. Lipid Search software processes data from both infusion MS/MS and LC-MS/MS data, and uses MS2 and/or MS3 data to identify lipids from a comprehensive database of more than one million species. The software integrates data from multiple samples or groups, and is intended for both novice and expert users.

“This agreement represents an ideal pairing of powerful lipidomics software with our family of high performance mass spectrometry and chromatography instruments,” said Dr. Yingying Huang, strategic marketing manager, metabolomics, Thermo Fisher Scientific “Together we provide a unique, powerful, and highly efficient workflow solution for the Lipidomics market. We’re committed to helping customers accelerate their research by freeing them to concentrate on their work rather than their tools.”

Lipid Search software can identify lipids from raw mass spectra generated by a wide range of mass spectrometers from major manufacturers. Its database provides very high coverage compared to other commercial lipidomics software. It accommodates a number of acquisition modes, including precursor ion scanning, neutral loss scanning and product ion scanning. Lipid Search also enables quantitation of identified lipids.

”Analysis of lipidomic data requires an enormous amount of energy and time,” said Takeshi Bamba, Ph.D., associate professor, Department of Biotechnology, Osaka University.” With Lipid Search, we can successfully automate that process, to dramatically enhance performance By simultaneously analyzing more than one million mass spectrometry data, we can uncover many previously unreported lipids.”

Lipids are a type of metabolite that performs a number of biological functions, including energy storage, cell signaling, and supporting cell membrane structure. The Lipidome, the profile of all the lipids present in a tissue sample, is studied to discover the mechanisms of metabolic diseases such as diabetes and hypertension, plus some cancers, neurodegenerative disorders and infectious diseases. Interest in lipidomics has been growing in recent years for biomarker discovery and drug development.

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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. GlycobiologyGlycobiology encompasses research into the biological functions, synthesis and structures of glycans, including glycoproteins, glycolipids, proteoglycans and free oligosaccharides. Mass spectrometers and their software are commonly used in the study of glycobiology, along with structure predicting tools, chromatography and NMR.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Software PlatformsSoftware platforms are useful for various stages of laboratory experiments from data collection to data storage and processing. For instance lab software is available for system control, data management, data analysis and qualification / validation.MetabolomicsMetabolomics is the study of small metabolites (the intermediates and products of metabolism). It involves the identification and quantification of cellular metabolites using analytical technologies such as GC, HPLC, NMR, and LC/MS.LipidsLipids are a diverse group of organic compounds that are insoluble in water, including fats, oils, and hormones. They are critical for cellular structure and energy storage. Explore lipid analysis tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.

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Thermo Fisher Scientific Signs Distribution Agreement with MKI for Lipidomics Software