Thermo Fisher Scientific Builds on 10 Years of Discoveries Powered by Orbitrap with Product Innovations at ASMS 2015
1 Jun 2015Thermo Fisher Scientific Inc., the world leader in serving science, this week is celebrating 10 years of scientific research and discoveries based on its industry-leading Orbitrap mass spectrometry technology. Orbitrap technology continues to spawn new and exciting product innovations, enabling customers in research and applied markets to advance scientific discovery and improve laboratory productivity.
“During that time, we have continued to invest in R&D, providing more customers in a broader range of industries with access to our industry-leading mass spectrometry platform. This week, we celebrate our customers’ success in driving advanced proteomics forward into the next decade and beyond.”
The Orbitrap celebration and innovative new technologies are among the highlights at the 63rd Annual American Society for Mass Spectrometry Conference, Booth 140, and at the Landmark Suite at the Renaissance Hotel in St. Louis.
“A decade ago at ASMS, Thermo Fisher introduced Orbitrap technology to the market, creating the opportunity for a new era in proteomics,” said Dan Shine, president, chromatography and mass spectrometry for Thermo Fisher. “During that time, we have continued to invest in R&D, providing more customers in a broader range of industries with access to our industry-leading mass spectrometry platform. This week, we celebrate our customers’ success in driving advanced proteomics forward into the next decade and beyond.”
Building on its legacy of innovation in mass spectrometry, Thermo Fisher introduces the new Thermo Scientific Orbitrap Fusion Lumos Tribrid Mass Spectrometer, the newest addition to the line of pioneering Thermo Scientific Orbitrap Tribrid mass spectrometers. Designed to expand researchers’ capabilities in advanced proteomics and metabolomics applications, including targeted, data-independent acquisition (DIA) and top-down analyses, the Orbitrap Fusion Lumos Tribrid has the industry’s highest level of sensitivity, delivering complete protein sequence coverage and allowing scientists to perform more inclusive analyses.
Also making its appearance at ASMS is the Thermo Scientific Q Exactive GC-MS/MS – the industry’s first instrument to integrate high-resolution gas chromatography (GC) and high-resolution accurate-mass (HRAM) Orbitrap mass spectrometry (MS). This new-generation system provides pharmaceutical, metabolomics, anti-doping and food safety laboratories with improved levels of productivity by combining the highest level of targeted and non-targeted detection and identification capabilities to GC-MS applications.
In response to customer requests for tools designed to manage, analyze and share the large volumes of scientific data generated in proteomics, the Thermo Fisher Cloud now supports proteomics-related data to complement existing data modules for Sanger sequencing and quantitative polymerase chain reaction (qPCR), connecting scientists, instruments and software in a collaborative, multi-disciplinary environment.
The anniversary celebration continues with the announcement of the winners of the 2015 Thermo Scientific Tandem Mass Tag (TMT) Research Award. This award recognizes excellence in proteomics and includes TMT reagents valued at $5,000 and designed to streamline global expression studies using mass spectrometry.
Addressing the need for innovation in applied markets, Thermo Fisher introduces the Thermo Scientific Pesticides Explorer Collection, a set of LC-MS solutions specifically tailored to fit the needs of laboratories performing routine quantitation, targeted screening and non-targeted analysis of pesticide residues in food matrices.
For increased productivity in the lab, the new Thermo Scientific Xcalibur 4.0 software is a unified platform for acquisition and analysis of MS data. This easy-to-use software creates a convenient and organized launch platform for new or previously installed Thermo Scientific software. It also provides direct access to the Xcalibur Apps Store, easy software updates and links to the mzCloud™, Thermo Fisher Cloud and Planet Orbitrap to access spectral libraries and new MS data.
In addition to introducing innovative new products, Thermo Fisher announced that New Objective’s PicoChip™ technology is now available on select Thermo Fisher mass spectrometry platforms, broadening the low-flow separation options available to proteomics, pharmaceutical and other researchers.
Rounding out this year’s ASMS highlights are:
- Thermo Scientific SMART Digest kit, a new tool for protein digestion substantially reducing preparation times and associated errors for biopharmaceutical and protein research applications;
- Thermo Scientific Vanquish UHPLC, offering improved performance in sample separation, throughput and ease-of-use for applications ranging from pharmaceutical QA/QC to food safety testing; and
- Fisher Chemical UHPLC-MS Optima solvents designed to address the trace analysis needs of chromatographers performing state-of-the-art UHPLC.
For more information about Thermo Fisher Scientific at ASMS 2015, please visit Booth 140, the Landmark Suite at the Renaissance Hotel.
*mzCloud is a trademark of HighChem LLC, Slovakia. PicoChip is a trademark of New Objective, Inc.
For more news on ASMS 2015 please click here.
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Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
Thermo Fisher ScientificTest new limits of detection, characterization and quantitation with the latest Tribrid™ mass spectrometer. The Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer is designed to expand performance in advanced proteomics, biopharma and metabolomics applications, including quantitation using isobaric tags, low level PTM analysis, data independent acquisition (DIA), and top down proteomics. The new instrument features enhanced sensitivity resulting in improved analyte detection, characterization and quantitation, enabling scientists to perform more comprehensive sample analyses faster and with better accuracy than ever before. Novel Orbitrap Fusion Lumos MS Features: Novel high-sensitivity API interface combines a High Capacity Transfer Tube and an Electrodynamic Ion Funnel for increased ion flux and lower limits of detection Advanced Active Beam Guide prevents neutrals and high velocity clusters from entering the resolving quadrupole Advanced Quadrupole Technology combines high selectivity and efficiency of transfer for selected ions symmetrically across the isolation window Advanced Vacuum Technology improves transmission of high molecular weight ions to the Orbitrap analyzer Novel ETD HD—high dynamic range ETD provides significantly increased fragment ion coverage Established Tribrid MS Features: Tribrid architecture — includes quadrupole mass filter, linear ion trap and Orbitrap mass analyzers Ultrahigh resolving power up to 500,000 FWHM, with isotopic fidelity up to 240,000 FWHM at m/z 200 Acquisition rates of up to 20 Hz for both Orbitrap and linear ion trap MSn analyses Full parallelization of MS and MSn analyses with intelligent ADAPT™ (All Dynamically Available Parallelizable Time) technology Synchronous Precursor Selection (SPS) for MS and MSn experiments significantly increases the number of peptides and proteins identified and improves quantitative accuracy when using isobaric mass tags Flexibility of fragmentation — CID, HCD and optional ETD and EThcD available at any stage of MSn with detection in either the Orbitrap or linear ion trap detector enables detailed structure determination of metabolites, glycans and other small molecules Universal Method provides maximal peptide identifications without method optimization for samples of unknown concentration, reducing sample and instrument time requirements for routine peptide identifi cation experiments Intuitive and flexible drag-and-drop user interface simplifies method development and enables unique and complex workflows
Thermo Scientific™ SMART Digest™ Kits
Thermo Fisher ScientificObtain high quality analytical results from protein digests by using Thermo Scientific™ SMART Digest™ Kits. A significant advance in sample preparation for biopharmaceutical and protein research, the kits provide fast and simple protein digestion with high reproducibility, high sensitivity, and high levels of data quality in a format that's compatible with automation. The SMART Digest Kits are a significant improvement over current in-solution protein digestion technologies, which are not reproducible, have poor sensitivity, and employ protracted methodologies not amenable to automation. Features: Easy and simple Significantly increased speed of sample processing. 3-step sample preparation. Easily automate entire protocol for high-throughput processing. Reliable results Increased reproducibility over existing protocols. Higher sensitivity. Higher data confidence.