Real Time Binding Analysis Made Easy with OpenPlex
2 May 2013HORIBA Scientific is pleased to announce the launch of OpenPlex, a flexible research platform for the real time analysis of label-free molecular interactions in a multiplex format.
OpenPlex uses Surface Plasmon Resonance imaging (SPRi) to monitor the binding of molecules to an array of receptors immobilized on a sensor chip. It can give qualitative (Yes/No binding) and quantitative information of the interactions such as concentration, affinity (KD), association and dissociation rates (kon, koff). Molecular interactions involving proteins, DNA, RNA, oligosaccharides, living cells, polymers or nanoparticles can be characterized and quantified.
OpenPlex is the evolution of SPRi-Lab+, the bench-top flexible label-free instrument from HORIBA Scientific. This instrument was designed for simple operation and is adapted to multiple applications covering physico-chemistry, biochemistry, biology and nanotechnology.
Different flow cell configurations are available, making the combination of label-free molecular interaction analysis to fluorescence or electrochemistry even easier. This new design will facilitate cutting-edge research, from nanotechnologies to biomedical research.
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OpenPlex - Flexible Surface Plasmon Resonance Imaging System
HORIBA ScientificDesigned to meet the demands of biologists, biochemists and biophysicists, the OpenPlex is a flexible surface plasmon resonance imaging system. OpenPlex is your companion for the development of label-free and multiplexed bio-assays and molecule detection. It is a robust and compact system designed for simple use and high versatility. Its open format, dedicated sensor chips and manual operation enable numerous types of experiments to be explored without compromise, covering chemistry, biochemistry, physico-chemistry and biomolecular interactions. Open your research areas with OpenPlex! Choose between three different flow cell configurations without concession: • Normal flow cell for standard surface plasmon resonance imaging experiments • Window flow cell, compatible with fluorescence measurements • Cuvette cell, compatible with electrochemistry measurements