New Large Capacity Bioprocessing Centrifuge Enhances Productivity and Reliability

Thermo Scientific Sorvall BIOS 16 centrifuge designed to provide simplified, flexible bioprocessing

22 Mar 2016
Alex Waite
Editorial Assistant

Product news

Designed to maximize productivity for bioprocessing customers, the new Thermo Scientific Sorvall BIOS 16 centrifuge offers an increased capacity of up to 16 L of cell culture product per run and unique design features to make working with large volumes easier and more convenient.

In the increasingly complex, regulated and fast-paced bioprocessing environment, users require a centrifuge with simple operation and high-throughput capabilities that deliver run-to-run reproducibility while maintaining sample integrity. These elements are essential to manufacturing products in a scalable, consistent and safe manner. When it comes to the development and manufacturing of biological products, the centrifuges used in the supporting separation and purification processes tend to be large in size and continuously used. As such, innovative and ergonomically designed platforms become high priority when choosing the best system.

The Thermo Scientific Sorvall BIOS 16 centrifuge includes several features designed to enhance the user experience, including:

  • Auto-Door function: Open and close the centrifuge door automatically using the simple push-button operation
  • Auto-Lid function: Instant rotor opening and closing with lid storage
  • Centri-Touch interface: Bright, highly visible and glove-friendly display simplifies run set-up
  • Accumulated Centrifugal Effect (ACE) function: Automatically adjust run time to account for and eliminate acceleration/deceleration variations that could otherwise lead to incomplete cell pelleting
  • Centri-Vue remote monitoring: Check run status or see available centrifuges from the mobile app
  • Eco-Spin technology: Take advantage of energy savings of up to 64% using wind shielded rotors

“For more than 60 years, Thermo Fisher Scientific has demonstrated application expertise across its centrifuge systems and the addition of the Sorvall BIOS 16 bioprocessing centrifuge builds upon that commitment to delivering innovative designs to meet specific user needs,” said Monica Manotas, VP/GM, growth, protection and separation products at Thermo Fisher Scientific. “Now, bioprocessing centers around the world can reap the benefits of this unique, user friendly system designed to provide high-throughput sample processing, simple, quick set-up and remote monitoring, energy savings, global safety standards and enhanced ergonomics with every run.”

The new Sorvall BIOS 16 bioprocessing centrifuge offers the flexibility to select higher capacity rotors or match existing workflows, with a choice of four swinging bucket rotors ranging from 6 x 1000 mL to 8 x 2000 mL. This product is listed with the US FDA, and complies with the latest global safety standards including UL and CE.

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CentrifugesCentrifuges are used to separate particulates suspended in a liquid via the application of a centrifugal force including cells, macromolecules, nanoparticles and precipitates. Centrifuges come in three sizes: microcentrifuges, benchtop and floor-standing centrifuges, depending on the volume and number of samples that require separation. When choosing a centrifuge, consider its maximum separation power indicated by its relative centrifugal force (RCF) value. Low force centrifuges reach a maximum RCF of 8,000 g, high-force centrifuges can reach maximum RCF values of 80,000 g. For extremely high forces, consider ultracentrifuges (up to 800,000 g). Refrigerated and vacuum centrifuges also known as concentrators are available for more specialized applications. A range of volumes are available for centrifuge tubes and microfuge tubes, depending on sample sizes. Find the best centrifuges in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample ManagementSample management systems include sample storage devices such as freezers and plate storers, sample environment enclosures and sample organization, retrieval and sorter systems. Useful system features include high-throughput, automation, robotic arms, automated liquid handling and associated database systems. Accessories in sample management include barcode scanners, heat sealers and tubes.Robotic InstrumentsRobotic instruments can be used for high-throughput automation of many lab processes. Such processes use instruments for assays like cell based assays and ELISA, for sample preparation like shakers, centrifuges and incubators, and for analysis such as sequencing and western blot analyzers. Useful features of robotic instruments include speed, reproducibility, barcode readers, software and automation.RegulatoryPharmaceutical regulations impact on all areas of drug development, manufacture and control and supply. Services are provided from the early stages of drug development and clinical trials through to dossier submission, approval and marketing. Regulatory also includes submission of analytical studies from the pharmaceutical product and safety. Quality ControlQuality control is needed in all production processes. Quality control is a monitoring procedure or set of procedures that are put in place to ensure that a manufactured product adheres to a defined set of quality criteria. Laboratory SafetyLaboratory safety is essential to the effective operation of all laboratories and is required to minimize the risk of harm during experiments. Guidelines, regulations, and equipment should be available in all laboratories to ensure that the working environment is safe and secure.CentrifugeEnergy