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New GeneGnome5 Chemiluminescent Imaging System Guarantees Scientists can Accurately Image Blots with Minimal System Training

Syngene
19 Jun 2011
bridget bridget
Laboratory Director

Product news

Syngene has unveiled its new GeneGnome5, a dedicated chemiluminescent imaging system designed to make precise imaging of chemiluminescent Western blots a simple, one click task.

The new GeneGnome5 has a high resolution, cooled camera inside a light tight cabinet that is fully integrated to a processor and flat screen monitor. The GeneGnome5 is quick and easy to set up as its fixed aperture lens means scientists don’t need to spend time adjusting the camera and they can load blots into the system’s slide-out drawer, view the image and capture it with just one click.

The GeneGnome5, which includes a white light for viewing coloured protein markers, generates images using Syngene’s new GeneSys image capture software. This unique software automatically selects the best conditions for imaging any blot, regardless of which chemiluminescent reagents scientists are using, to produce a high-quality image from even poorly expressed proteins.

The compact GeneGnome5 requires very little bench space because its integral processor means an external computer is not necessary for image capture. For analysing bands and spots, the system comes with GeneTools, Syngene’s powerful image analysis software, which saves valuable time by calculating in seconds, data such as the molecular weight and quantity of proteins on the blot.

Laura Sullivan, Syngene’s Divisional Manager stated: “Many researchers find achieving the optimum conditions for accurately imaging close protein bands or spots on chemi blots can be very time consuming. We have solved the problem by integrating the revolutionary GeneSys image capture software and the latest high resolution optics into our award winning GeneGnome. This takes chemi-luminescent imaging technology to unrivalled levels of sensitivity, so that scientists using the new GeneGnome5, even those unfamiliar with analysing chemiluminescent Western blots, can look forward to obtaining accurate results time after time.”

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Western BlottingWestern blotting equipment is used to transfer and identify specific proteins within a sample, reveal protein modifications, as well as give a semi-quantitative estimation of their concentration. Western blotting equipment includes all apparatus necessary to transfer proteins from gel to membrane and subsequent processing steps. Protein transfer can be performed by electroblotting with wet, semi-dry and dry transfer systems onto nitrocellulose and PVDF membranes. Blocking, washing and labeling of membranes follows, involving buffers, blocking reagents, blotting / incubation trays, labeling reagents, immunoblotting assays, antibodies and conjugates. Automated equipment for these steps is available to accelerate your lab workflow. Finally, detection and imaging of proteins can be conducted using gel documentation and imaging systems. Find the best western blotting equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Gel Doc / Image AnalysisGel documentation (gel doc) or gel imaging systems are used for the analysis of proteins, antibodies and nucleic acid immobilized in polyacrylamide or agarose gels, membranes or microarrays. Explore a range of a gel imaging systems, densitometers, scanners, transilluminators or UV lamp + CCD cameras for your image analysis solutions. Colorimetric, fluorescent and/or radioisotopic samples can be visualized and documented for further analysis. See gel doc / Image analysis software for quantitative 1D and 2D analysis of your samples. Find the best gel doc / image analysis products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :

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New GeneGnome5 Chemiluminescent Imaging System Guarantees Scientists can Accurately Image Blots with Minimal System Training