Dionex Introduces the UltiMate 3000 Titanium LC System for Biomolecule Analysis

6 Mar 2008
Greg Smith
Analyst / Analytical Chemist

Product news

Dionex expands its family of industry-leading HPLCs with the fully biocompatible UltiMate® 3000 Titanium system. The UltiMate 3000 Titanium is ideal for analyzing biomolecules, such as monoclonal antibodies. With chemically inert flow paths, the system ensures that precious sample is not denatured or degraded by reacting with flow path components during analysis. Now, chromatographers can run precise, fast gradient separations with the shortest possible cycle time in single-pump or dual-pump configurations—without sample interacting with flow path components.

The UltiMate 3000 Titanium system features a titanium fluidics pump, a PEEK™ fluidics autosampler and switching valves, and PEEK flow cells. It ensures full compatibility with all biological buffers and labile compounds and aids longevity of the system—particularly with use of harsh salts and high or low pH solutions. System biocompatibility protects protein integrity and post-translational modifications during separations.

The UltiMate 3000 Titanium is part of Dionex Intelligent LC (LCi) solutions with Chromeleon® chromatography management software and the excel­lent separations chemistries featured in the Dionex Acclaim®, PepSwift™, ProSwift™, and ProPac® columns.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.