Quantitation of 12 Benzodiazepines and Metabolites in Urine Using Ultrahigh Resolution LC-MS for Forensic Toxicology Use

This application note shows that the Thermo Scientific Exactive benchtop LC-MS instrument provides quantitative analysis of 12 benzodiazepines, from 10 ng/mL to 5000 ng/mL in urine, using ultrahigh resolution full scan data acquisition in a 6-minute method. The accuracy, precision, LOQ, and linearity range of the method meet the demands of today’s forensic toxicology laboratories.